DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment JhI-21 and zmp:0000001267

DIOPT Version :9

Sequence 1:	NP_001245996.1	Gene:	JhI-21 / 34624	FlyBaseID:	FBgn0028425	Length:	500	Species:	Drosophila melanogaster
Sequence 2:	XP_021323160.1	Gene:	zmp:0000001267 / 100537392	ZFINID:	ZDB-GENE-140106-227	Length:	470	Species:	Danio rerio

Alignment Length:	450	Identity:	175/450 - (38%)
Similarity:	282/450 - (62%)	Gaps:	5/450 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 EKIVLKRKLTLINGVAIIVGTIIGSGIFIAPTGVFIYTESVGSSLLIWLTCGILSTIGALCYAEL 97
            ||:.|:|:|.|.:.|::..|.:||||||::|..|.:|..|.|:||:||..||::....|..|||:
Zfish     5 EKLNLRRELGLASAVSLAAGVMIGSGIFMSPQFVLVYVGSSGASLIIWAVCGVVCMCTAFSYAEI 69

  Fly    98 GTCITRSGGDYAYLLVSFGPLVGFLRLWIALLIIRPTTQTIVALSFAHYAVKPFFPECDPPQNAV 162
            ||.|..|||:|.|:|..:||.:.|:..:..:.:::|.:....:||||.|||.||:|.|.||...|
Zfish    70 GTIIRESGGNYIYILRIYGPCLAFVLSFTTMFLMKPLSIIAGSLSFAKYAVAPFYPGCTPPILVV 134

  Fly   163 KLLAAICLTLLTTINCLSVKVSMKVQDVFTVGKLLALIMIILSGLYYMATGELENFRNPWEGIYT 227
            |.:||.|:.:::|||.|:|:.:|..|.||.|.||:.|::|::.|:..:|.|..|:..|.......
Zfish   135 KCIAAACVLVISTINVLNVRFAMASQVVFMVAKLVGLMIIVIGGIITVAQGNCESLCNSKSAFAD 199

  Fly   228 AR----NIGYAFYSGLFAFGGWNYLNFVTEELQDPYKNLPRAIWIAMPLVTSIYVLVNLAYFAVV 288
            |:    .:|.|.|..|:::.||:.:|.|.||::.|..|||||:.||:|:||.:|:|||::|...:
Zfish   200 AKLSISTVGMALYQCLWSYAGWSNINNVIEEVKRPEVNLPRALMIAIPMVTILYLLVNVSYLVAM 264

  Fly   289 NKPEMLSSLAVAVTFGNRVFGPLAFMVPIFVALSTFGGVNGVLFTSARLFATGAQEGHLPKFFQL 353
            :..||:||.|||||:||:|.|...:::.|..|||:||.:||..|:..|:....|:|||:|....:
Zfish   265 SPAEMISSSAVAVTWGNKVLGGWGWVMSIAAALSSFGSLNGSFFSGGRVCYVAAREGHMPDILAM 329

  Fly   354 FHVKQQTPIPSLIFTCLMSLLMLLTDNVYQLINYFSSVLWLSVVASIAGMLWLRHKRPDLPRPIK 418
            .|:.:.||.|:|||..:::|::|:..:...::|:.|...|.....:::|:|:|:.|:|:|||.|.
Zfish   330 AHMHRLTPSPALIFNTVIALIVLIPGDFQAIVNFLSFTAWFFYGVTLSGLLYLKIKKPELPRAIS 394

  Fly   419 VHLALPITFMVSCVTLVLLPNLEEPQ-NLLIGIGITLAGIPFYYAFIARKKKPKCYGRLS 477
            |.:.|||..:::.|.|||.|.:::|| ..|..:...|:.|..|..||..|..|....:|:
Zfish   395 VPIILPIVALLAAVFLVLAPIIDDPQIEYLYAVIFILSSIVIYIPFIHFKLFPGMLNKLT 454

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
JhI-21	NP_001245996.1	AA_permease_2	27..494	CDD:330980	175/449 (39%)
zmp:0000001267	XP_021323160.1	AA_permease_2	5..468	CDD:330980	175/449 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1287
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	1	1.010	-	-		D621852at2759
OrthoFinder	1	1.000	-	-		FOG0000064
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X75
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.830