DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment JhI-21 and slc7a8b

DIOPT Version :9

Sequence 1:	NP_001245996.1	Gene:	JhI-21 / 34624	FlyBaseID:	FBgn0028425	Length:	500	Species:	Drosophila melanogaster
Sequence 2:	XP_001346314.3	Gene:	slc7a8b / 100007990	ZFINID:	ZDB-GENE-030616-586	Length:	501	Species:	Danio rerio

Alignment Length:	468	Identity:	229/468 - (48%)
Similarity:	322/468 - (68%)	Gaps:	10/468 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 DGEEKIVLKRKLTLINGVAIIVGTIIGSGIFIAPTGVFIYTESVGSSLLIWLTCGILSTIGALCY 94
            |||..:.||:::.|::...|:||.|||||||::|.||...:.|||.:|::|:..||::.||||||
Zfish    19 DGEPAVTLKKEIGLLSACGIVVGNIIGSGIFVSPKGVLENSGSVGLALIVWILTGIITAIGALCY 83

  Fly    95 AELGTCITRSGGDYAYLLVSFGPLVGFLRLWIALLIIRPTTQTIVALSFAHYAVKPFFPECDPPQ 159
            ||||..|.:|||||:|:...||.|.||||||||:|:|.||.|.::||:||:||::|.||.|.||:
Zfish    84 AELGVTIPKSGGDYSYVNDIFGGLAGFLRLWIAVLVIYPTNQAVIALTFANYALQPLFPSCFPPE 148

  Fly   160 NAVKLLAAICLTLLTTINCLSVKVSMKVQDVFTVGKLLALIMIILSGLYYMATG-----ELENFR 219
            .|:.||||:||.|||.|||.||:.:.:||||||.||||||.:||:.|:..:..|     |.|:..
Zfish   149 RALGLLAAVCLLLLTWINCSSVRWATRVQDVFTTGKLLALGLIIIMGIVQICKGHFYWLEPEHAF 213

  Fly   220 NPWEGIYTARNIGYAFYSGLFAFGGWNYLNFVTEELQDPYKNLPRAIWIAMPLVTSIYVLVNLAY 284
            :|.:. |....|..|...|.||:.|||:||:|||||.|||:||||||:|::||||.:||..|:||
Zfish   214 HPLQP-YDMGRIALAVLQGSFAYAGWNFLNYVTEELIDPYRNLPRAIFISIPLVTFVYVSANIAY 277

  Fly   285 FAVVNKPEMLSSLAVAVTFGNRVFGPLAFMVPIFVALSTFGGVNGVLFTSARLFATGAQEGHLPK 349
            ...::..|:|:|.|||||||.::.|.:::::||.|||||||||||.||||:|||..||:|||||:
Zfish   278 VTAMSPQELLASNAVAVTFGEKLLGVMSWLMPISVALSTFGGVNGSLFTSSRLFFAGAREGHLPR 342

  Fly   350 FFQLFHVKQQTPIPSLIFTCLMSLLMLLTDNVYQLINYFSSVLWLSVVASIAGMLWLRHKRPDLP 414
            ...:.||.:.||||:|:.||:.:||||...::|.||||...:.:|....::||.:.||.:.||:.
Zfish   343 LLAMIHVNRCTPIPALLITCISTLLMLCVSDIYTLINYVGFINYLFYGVTVAGQIVLRIREPDIY 407

  Fly   415 RPIKVHLALPITFMVSCVTLVLLPNLEEPQNLLIGIGITLAGIPFYYAFIARKKKPKCY----GR 475
            |||||.||.|..|::....|::.....||....||:.|.|:|:|.|...|..:.|||.:    .|
Zfish   408 RPIKVSLAWPAVFLIFWAFLLIFSLYSEPVVCCIGLAIMLSGVPVYLFGIYWENKPKSFSSFVAR 472

  Fly   476 LSNSVVEICRAIF 488
            |::...::|..::
Zfish   473 LTHLGQKLCLVVY 485

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
JhI-21	NP_001245996.1	AA_permease_2	27..494	CDD:330980	229/468 (49%)
slc7a8b	XP_001346314.3	AA_permease_2	9..488	CDD:330980	229/468 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1287
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	1	1.010	-	-		D339093at33208
OrthoFinder	1	1.000	-	-		FOG0000064
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100314
Panther	1	1.100	-	-	O	PTHR11785
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X75
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	9	8.830