Protein Alignment PLCXD and PLCXD1

DIOPT Version :10

• Sequence 1: NP_609541.1
• Gene: PLCXD / 34623
• FlyBaseID: FBgn0032402
• Length: 482
• Species: Drosophila melanogaster
• Sequence 2: NP_060860.1
• Gene: PLCXD1 / 55344
• HGNCID: 23148
• Length: 323
• Species: Homo sapiens
• Alignment Length: 333
• Identity: 76/333 - (22%)
• Similarity: 143/333 - (42%)
• Gaps: 45/333 - (13%)

  Fly   179 IDAQGNILAKTCLKVFPRWMNDLKSKIGEMRLRDLFIPGTHDSGSYRPNFD-------------- 229
            :.|..:.....|......||:.|..::.::.|..|.|||:||:.:|..|..
Human     5 VSASNSFSRLHCRNANEDWMSALCPRLWDVPLHHLSIPGSHDTMTYCLNKKSPISHEESRLLQLL 69

  Fly   230 ----PLLRESLVTKYALTQDDDIRGQLMHGVRYLDIRVGY-YRNSPDPFFIYHGITKQRPLQEVI 289
                |.:...:|.|:::||..|:..||..||||||:|:.: ...|.......|.:.....:::.:
Human    70 NKALPCITRPVVLKWSVTQALDVTEQLDAGVRYLDLRIAHMLEGSEKNLHFVHMVYTTALVEDTL 134

  Fly   290 NQVRDFV-YETNEIIIFGLKEFPVGFGKGLG--VHRLLISYLRDQLKDLIAHPSLTWGASLRDIW 351
            .::.::: ....|::|...:.|     :||.  :|..|::.:::...|::......  .:||.:|
Human   135 TEISEWLERHPREVVILACRNF-----EGLSEDLHEYLVACIKNIFGDMLCPRGEV--PTLRQLW 192

  Fly   352 ARRQNVFLAYDHEAMVEEFPDVLFGSVEQRWGNKQTWDQLETYLRNVNDFDVSRFSSRP----VS 412
            :|.|.|.::|:.|:.:....: |:..|...|||:...:.|..||      :..:...||    |:
Human   193 SRGQQVIVSYEDESSLRRHHE-LWPGVPYWWGNRVKTEALIRYL------ETMKSCGRPGGLFVA 250

  Fly   413 DMAELTPETWDVILDKTGGLRKMADNVNWRISQLYRNEL---GTN-ANIVSADFIRGTTLVETAI 473
            .: .||.....|:...:..|.||......|:|...|.:.   |:. .||::.|||.....|...|
Human   251 GI-NLTENLQYVLAHPSESLEKMTLPNLPRLSAWVREQCPGPGSRCTNIIAGDFIGADGFVSDVI 314

  Fly   474 EYNARKIY 481
            ..|.:.::
Human   315 ALNQKLLW 322

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PLCXD	NP_609541.1	PI-PLCXDc_CG14945_like	202..479	CDD:176559	71/306 (23%)
PLCXD1	NP_060860.1	PI-PLCXD1c	27..317	CDD:176555	71/304 (23%)