DRSC/TRiP Functional Genomics Resources

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Protein Alignment Plzf and Zbtb8a

DIOPT Version :9

Sequence 1:NP_001285862.1 Gene:Plzf / 34622 FlyBaseID:FBgn0032401 Length:469 Species:Drosophila melanogaster
Sequence 2:NP_082879.1 Gene:Zbtb8a / 73680 MGIID:1920930 Length:434 Species:Mus musculus


Alignment Length:489 Identity:100/489 - (20%)
Similarity:162/489 - (33%) Gaps:120/489 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly    14 HQPLHSKVSNYLNNQRRTGQFCD--LLLELDSDDSLSLSVHFCVLAAQSQFINSNQKQQQFSIHN 76
            ||   |.:...||.|||...|||  :|:|     ......|..||.|.|.:......|.......
Mouse     6 HQ---SYLLQQLNEQRRQDVFCDCSILVE-----GKVFKAHRNVLFASSGYFKMLLSQNSRETSQ 62

  Fly    77 PLKITIRNFSCTQCLHTIVDFFYEDLVSVSKEHELHFRELAQILAVTELLNL------------- 128
            |...|.:.|| ......|:||.|...:|::.::.:.....|..|.:|:::::             
Mouse    63 PTTATFQTFS-PDTFTVILDFVYSGKLSLTGQNVIEVMSAASFLQMTDVISVCKTFIKSSLDISE 126

  Fly   129 ------YQLQPLGEAKEATEIP------------APGEAQPNPDPEKKAEAVFENRQSYFKLKNP 175
                  :.|..........|.|            :| .:..:|||.|..........|....:.|
Mouse   127 KEKDRYFSLSDKDTGSNGVERPPFYSSSWQEEGGSP-HSHVSPDPGKPWNKYGYPPASQRSPQRP 190

  Fly   176 RAVKSSSKVNYCIGCDFKCYQVQKMIEHMGSCEPSHLICSLCEVGFLDWREYDTHLRRHSGDLRK 240
            .|.....|            :..|..:|:...:||.::                |.:...|:.: 
Mouse   191 LAKHEQRK------------EPSKKAKHVRLPQPSEVV----------------HFKPGKGEAQ- 226

  Fly   241 PFFCLQCGIRFNTRAALLVHQPKHSTETPHICPHCGKGFKWKQGLSNHILVHNPEK----QMLCD 301
                        |.:...|.|.:..............||::.|| .:.|....|:.    :..|.
Mouse   227 ------------TDSGNHVSQSEEQVPVDAEVDPAPAGFQYSQG-PDGIARSFPDDLTRLRFKCP 278

  Fly   302 VCGYSTTHMKALKSHKLLHTGEF-FACTVSGCKHRANRKENLKLHIETHKQGRDFICEVCGCKFS 365
            .|.:.......||.|...||||. :.|  ..|..|.:|.::|..|..|..|....||..|     
Mouse   279 FCTHVVKRKADLKRHLRCHTGERPYPC--QACGKRFSRLDHLSSHFRTIHQACKLICRKC----- 336

  Fly   366 QSKNLKRHALKHT----ENGPNRYK-CQLC----GFSSHRSD-KMKEH-VQRVHTEKPVQLELSE 419
                 |||....|    :.|..||: |..|    |..|..:| :.::| ......:|..:..|||
Mouse   337 -----KRHVTDLTGQVVQEGTRRYRLCNECLADVGMESLPADLEAEQHRTAPADGDKDCRWHLSE 396

  Fly   420 TVDSSFPD-------DFELPVIETSPKKKPKSVK 446
            ..:.|:.:       |..:..::.|.:::.|.:|
Mouse   397 EENRSYVEIVEDGSADLVIQQVDDSEEEEEKEIK 430

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PlzfNP_001285862.1 COG5048 <193..403 CDD:227381 47/224 (21%)
C2H2 Zn finger 214..234 CDD:275368 1/19 (5%)
C2H2 Zn finger 244..264 CDD:275368 3/19 (16%)
C2H2 Zn finger 272..292 CDD:275368 5/19 (26%)
C2H2 Zn finger 300..320 CDD:275368 5/19 (26%)
C2H2 Zn finger 330..349 CDD:275368 5/18 (28%)
C2H2 Zn finger 357..377 CDD:275368 5/19 (26%)
C2H2 Zn finger 387..408 CDD:275368 6/26 (23%)
Zbtb8aNP_082879.1 BTB 14..119 CDD:279045 28/110 (25%)
BTB 25..122 CDD:197585 21/102 (21%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 134..238 21/145 (14%)
COG5048 275..>328 CDD:227381 16/54 (30%)
C2H2 Zn finger 277..297 CDD:275368 5/19 (26%)
zf-H2C2_2 289..314 CDD:290200 10/26 (38%)
C2H2 Zn finger 305..324 CDD:275368 6/20 (30%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

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