DRSC/TRiP Functional Genomics Resources

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Protein Alignment Plzf and Zbtb42

DIOPT Version :9

Sequence 1:NP_001285862.1 Gene:Plzf / 34622 FlyBaseID:FBgn0032401 Length:469 Species:Drosophila melanogaster
Sequence 2:NP_001119774.1 Gene:Zbtb42 / 691556 RGDID:1582758 Length:420 Species:Rattus norvegicus


Alignment Length:477 Identity:99/477 - (20%)
Similarity:152/477 - (31%) Gaps:153/477 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly    16 PLHS-KVSNYLNNQRRTGQFCDLLLELDSDDSLSLSVHFCVLAAQSQFINSNQKQQQFSIHNPLK 79
            |.|. ::...|..||..|..||..: |..|  .....|..||||.|.:.:...:.|..|..:.::
  Rat     4 PEHGVRLLGRLRQQRELGFLCDCTV-LVGD--ARFPAHRAVLAACSVYFHLFYRDQPASSRDTVR 65

  Fly    80 -----ITIRNFSCTQCLHTIVDFFYEDLVSVSKEHELHFRELAQILAVTELLNLYQLQPL--GEA 137
                 :|:..||      .::||.||..:      :||...:..:||....|::|.:..:  |..
  Rat    66 LNGDIVTVPAFS------RLLDFMYEGRL------DLHSLPVEDVLAAASYLHMYDIVKVCKGRL 118

  Fly   138 KE----------ATEIPA----------PGEAQPNP---DPEKKAEAVF-------------ENR 166
            ::          .||:|.          |...|..|   .|....:||.             |..
  Rat   119 RKKDPDLETRTLGTELPGQTPHPLPSWPPAFCQATPKAKPPSLGVKAVHPLPKFGPPSWQVSEES 183

  Fly   167 QSYFKLK---NPRAVKSSSKVNYCIGCDFKCYQVQKMIEHMGSCEPSHLICSLCEVGFLDWREYD 228
            .....|.   .||..::...   |:....:|..:|:..:.:...|..            .:.|.|
  Rat   184 SGALDLSLKPGPRPEQAHPP---CLLQTSQCSSIQQGAQPLVKAEQD------------SFSEQD 233

  Fly   229 THLRRHSGDLRKPFFCLQC--GIRFNTRAALLVHQPKHSTETPH--------------------- 270
            :. ...|.|...|..|...  |:..|.       :|.|...|..                     
  Rat   234 SS-SPQSADRSPPPVCASAARGLAVNL-------EPLHIQGTGSQQLGLHAEPVVDSEDLGPGRH 290

  Fly   271 --ICPHCGKGFKWKQGLSNHILVHNPEKQML------------CDVCGYSTTHMKALKSHKLLHT 321
              |||.|.|.|.....|..|:..|..|:..:            |.:|                  
  Rat   291 LCICPLCCKLFPSTHALQPHLSAHFRERDSVRTRLSPEGAVPTCPLC------------------ 337

  Fly   322 GEFFACTVSGCKHRANRKENLKLHIETHKQGRDFICEVCGCKFSQSKNLKRHALKHTENGPNRYK 386
            .:.|:||.:           ||.|..||...:.:.|..||..|..|.||.|||:.||...|  :.
  Rat   338 SKTFSCTYT-----------LKRHERTHSGEKPYTCVQCGKSFQYSHNLSRHAVVHTREKP--HA 389

  Fly   387 CQLCGFSSHRSDKMKEHVQRVH 408
            |:.|.....:|..:..||::.|
  Rat   390 CRWCERRFTQSGDLYRHVRKFH 411

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PlzfNP_001285862.1 COG5048 <193..403 CDD:227381 50/246 (20%)
C2H2 Zn finger 214..234 CDD:275368 2/19 (11%)
C2H2 Zn finger 244..264 CDD:275368 4/21 (19%)
C2H2 Zn finger 272..292 CDD:275368 7/19 (37%)
C2H2 Zn finger 300..320 CDD:275368 2/19 (11%)
C2H2 Zn finger 330..349 CDD:275368 3/18 (17%)
C2H2 Zn finger 357..377 CDD:275368 10/19 (53%)
C2H2 Zn finger 387..408 CDD:275368 5/20 (25%)
Zbtb42NP_001119774.1 BTB_POZ_ZBTB42 1..129 CDD:349737 32/139 (23%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 174..204 4/32 (13%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 216..248 6/44 (14%)
C2H2 Zn finger 294..314 CDD:275368 7/19 (37%)
COG5048 334..>388 CDD:227381 23/84 (27%)
C2H2 Zn finger 334..354 CDD:275368 8/48 (17%)
zf-H2C2_2 347..369 CDD:404364 8/21 (38%)
C2H2 Zn finger 362..382 CDD:275368 10/19 (53%)
C2H2 Zn finger 390..408 CDD:275368 4/17 (24%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

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