DRSC/TRiP Functional Genomics Resources

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Protein Alignment Plzf and zbtb8a

DIOPT Version :9

Sequence 1:NP_001285862.1 Gene:Plzf / 34622 FlyBaseID:FBgn0032401 Length:469 Species:Drosophila melanogaster
Sequence 2:NP_001035340.2 Gene:zbtb8a / 678523 ZFINID:ZDB-GENE-060421-5153 Length:459 Species:Danio rerio


Alignment Length:451 Identity:98/451 - (21%)
Similarity:162/451 - (35%) Gaps:86/451 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly     6 TMQSIPTLHQPLHSKVSNYLNNQRRTGQFCD--LLLE-----LDSDDSLSLSVHFCVLAAQSQFI 63
            |...:..:||   |.:...|:.||:...|||  :|:|     ...:.....|.:|.:|..|....
Zfish    28 TSADMSAIHQ---SCLLKQLDQQRKQELFCDCSVLVEGQIFHAHRNVLYGSSGYFRMLLTQGAKD 89

  Fly    64 NSNQKQQQFSIHNPLKITIRNFSCTQCLHTIVDFFYEDLVSVSKEHELHFRELAQILAVTELLNL 128
            ..:.....|.:.:|...||           |:||.|      |.:.||:...:.::::....|.:
Zfish    90 TVDSVSASFDVFSPDIFTI-----------ILDFIY------SGQLELNSSNVIEVMSAASYLQM 137

  Fly   129 YQLQPLGEA--KEATEIPAPGEAQPNPDPEKKAEAVFEN------RQSYFKLKNPRAVKSSSKVN 185
            ..:....:|  |...||      ....|.|.:...:.||      |:|..:..|...|..||:..
Zfish   138 NDVISYCKAFIKSFLEI------STKEDDENRYLCLSENSSLQDRRESTIEPSNMCDVSMSSQSR 196

  Fly   186 YCIGCDFKCYQVQKMIEHMG-SCEPSHLICSLCEVGFLDWREYDTHL--RRHSGDLRKPFFCLQC 247
            .   .|.:....|...:..| |.:||.|..:......|: .:|.:.|  ||..|.          
Zfish   197 L---WDEEQEDDQPQEDFGGTSPQPSGLQHNSPAQSSLE-EQYSSVLPERRRRGS---------- 247

  Fly   248 GIRFNTRAALLVHQPKHSTETPHICPHCG-KGFKWKQGLSNHILV-------HNPEKQMLCDVCG 304
              |..|.::.||.:.....:...:..||. |..:....|.:.:.|       ..|..:..|..|.
Zfish   248 --RKRTASSRLVAEDTSLIDLQGVVSHCSQKADELYANLPSIVGVVGMFNKDATPSMRYKCPFCT 310

  Fly   305 YSTTHMKALKSHKLLHTGEF-FACTVSGCKHRANRKENLKLHIETHKQGRDFICEVCGCKFSQSK 368
            ::......||.|...||||. :.|  ..|..|..|.|:|:.|.||..|.|..:|..|        
Zfish   311 HTVKRKADLKRHLRCHTGERPYPC--QACSKRFTRLEHLRSHFETIHQARKLVCRKC-------- 365

  Fly   369 NLKRHAL----KHTENGPNRYK-CQLCGFSSHRSDKMKEHVQRVHTEKPVQLELSETVDSS 424
              |||..    :....|..:|: |.:|...|..:|.:.:.......::.:.|.:.|.:..:
Zfish   366 --KRHVTEVSGRVVSEGTRKYRLCDVCIQESGYNDLITDETDGNEDKEGLLLGVDEDMSEN 424

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PlzfNP_001285862.1 COG5048 <193..403 CDD:227381 53/226 (23%)
C2H2 Zn finger 214..234 CDD:275368 4/21 (19%)
C2H2 Zn finger 244..264 CDD:275368 4/19 (21%)
C2H2 Zn finger 272..292 CDD:275368 5/27 (19%)
C2H2 Zn finger 300..320 CDD:275368 5/19 (26%)
C2H2 Zn finger 330..349 CDD:275368 7/18 (39%)
C2H2 Zn finger 357..377 CDD:275368 5/23 (22%)
C2H2 Zn finger 387..408 CDD:275368 4/20 (20%)
zbtb8aNP_001035340.2 BTB 44..149 CDD:279045 25/121 (21%)
BTB 55..152 CDD:197585 21/113 (19%)
COG5048 304..>357 CDD:227381 18/54 (33%)
C2H2 Zn finger 306..326 CDD:275368 5/19 (26%)
zf-H2C2_2 318..343 CDD:290200 10/26 (38%)
C2H2 Zn finger 334..355 CDD:275368 9/22 (41%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
00.000

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