DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Plzf and Sry-beta

DIOPT Version :9

Sequence 1:	NP_001285862.1	Gene:	Plzf / 34622	FlyBaseID:	FBgn0032401	Length:	469	Species:	Drosophila melanogaster
Sequence 2:	NP_001303451.1	Gene:	Sry-beta / 43570	FlyBaseID:	FBgn0003511	Length:	356	Species:	Drosophila melanogaster

Alignment Length:	393	Identity:	88/393 - (22%)
Similarity:	138/393 - (35%)	Gaps:	83/393 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 CVLAAQSQFINSNQKQQQFSIHNPLKITIRNFSCTQCLHTIVDFFYEDLVSVSKEHELHFRELAQ 118
            |::....:.|....|..:..|:..|::...:.:|..||..:  |.|:.||          |.|:|
  Fly    26 CIVPGTFKPIKDILKYFEKIINQRLELLPNSAACRDCLEYL--FNYDRLV----------RNLSQ 78

  Fly   119 I--LAVTELLNLYQLQPLGEAK-----------------EATEIPAPGEAQPNPDPEKKAEAVFE 164
            :  .....||...|::...|.|                 :||.:..| |.||..:.|.:.....|
  Fly    79 VQRQIADALLGCRQVEGKAETKQQAAKRARVQVPAFKIVQATALKEP-ERQPGEEDECEEFMKEE 142

  Fly   165 NRQSYFKLKNPRAVKSSSKVNYCIGCDFKCYQVQKMIEHMGSCEPSHLICSLCEVGFLDWREYDT 229
            .....|:...|.....||:..:                   ..|.:.:.|.:|...|......:.
  Fly   143 MLDEEFQFSEPDDSMPSSEEEF-------------------FTETTEIPCHICGEMFSSQEVLER 188

  Fly   230 HLRRHSGDLRKPFFCLQCGIRFNTRAALLVHQPKHSTETPHICPHCGKGFKWKQGLSNHILVHNP 294
            |::..:....:...|..||::......|.:|...|..:|...|.:|.|.|..|:.:..|:.||..
  Fly   189 HIKADTCQKSEQATCNVCGLKVKDDEVLDLHMNLHEGKTELECRYCDKKFSHKRNVLRHMEVHWD 253

  Fly   295 EKQMLCDVCGYSTTHMKALKSHKLLHTGEFFACTVSGCKHRANRKENLKLHIETHKQGRDFICEV 359
            :|:..||.||...:....:.:|.:.|..|                ||.            .||||
  Fly   254 KKKYQCDKCGERFSLSWLMYNHLMRHDAE----------------ENA------------LICEV 290

  Fly   360 CGCKFSQSKNLKRHALKHTENGPNRYKCQLCGFSSHRSDKMKEHVQRVH--TEKPVQLELSETVD 422
            |..:|...:..|.|...|..:.| ||.|..|..|......:|.| :|||  .|||...|..|...
  Fly   291 CHQQFKTKRTYKHHLRTHQTDRP-RYPCPDCEKSFVDKYTLKVH-KRVHQPVEKPESAEAKEATV 353

  Fly   423 SSF 425
            :.|
  Fly   354 TFF 356

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Plzf	NP_001285862.1	COG5048	<193..403	CDD:227381	46/209 (22%)
		C2H2 Zn finger	214..234	CDD:275368	4/19 (21%)
		C2H2 Zn finger	244..264	CDD:275368	5/19 (26%)
		C2H2 Zn finger	272..292	CDD:275368	6/19 (32%)
		C2H2 Zn finger	300..320	CDD:275368	5/19 (26%)
		C2H2 Zn finger	330..349	CDD:275368	2/18 (11%)
		C2H2 Zn finger	357..377	CDD:275368	7/19 (37%)
		C2H2 Zn finger	387..408	CDD:275368	6/20 (30%)
Sry-beta	NP_001303451.1	C2H2 Zn finger	203..223	CDD:275368	5/19 (26%)
		C2H2 Zn finger	231..251	CDD:275368	6/19 (32%)
		C2H2 Zn finger	259..308	CDD:275368	17/76 (22%)
		C2H2 Zn finger	288..303	CDD:275370	5/14 (36%)
		zf-C2H2	315..337	CDD:278523	7/22 (32%)
		C2H2 Zn finger	317..337	CDD:275368	6/20 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45446671
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030