DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Plzf and CG4424

DIOPT Version :9

Sequence 1:	NP_001285862.1	Gene:	Plzf / 34622	FlyBaseID:	FBgn0032401	Length:	469	Species:	Drosophila melanogaster
Sequence 2:	NP_650859.3	Gene:	CG4424 / 42390	FlyBaseID:	FBgn0038765	Length:	345	Species:	Drosophila melanogaster

Alignment Length:	166	Identity:	52/166 - (31%)
Similarity:	76/166 - (45%)	Gaps:	18/166 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   260 HQPKHSTETP----------HICPHCGKGFKWKQGLSNHILVHNPEKQMLCDVCGYSTTHMK-AL 313
            :.|..||..|          |:|..||.|:..|..|..|:..||.|:...|::| :.:.|:. .|
  Fly   167 YPPPASTPPPAPAGAVKGKLHVCAICGNGYPRKSTLDTHMRRHNDERPYECEIC-HKSFHVNYQL 230

  Fly   314 KSHKLLHTG-EFFACTVSGCKHRANRKENLKLHIETHKQGRDFICEVCGCKFSQSKNLKRHALKH 377
            |.|...||| :.:.|..  |:.....:.:|..|..||:..|.:.|:.||.||:.:..||.|...|
  Fly   231 KRHIRQHTGAKPYTCQY--CQRNFADRTSLVKHERTHRNERPYACKTCGKKFTYASVLKMHYKTH 293

  Fly   378 TENGPNRYKCQLCGFSSHRSDKMKEHVQ-RVHTEKP 412
            |  |...:.||||..|..|...:..|:| :.|...|
  Fly   294 T--GEKPHICQLCNKSFARIHNLVAHLQTQQHINDP 327

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Plzf	NP_001285862.1	COG5048	<193..403	CDD:227381	48/154 (31%)
		C2H2 Zn finger	214..234	CDD:275368
		C2H2 Zn finger	244..264	CDD:275368	1/3 (33%)
		C2H2 Zn finger	272..292	CDD:275368	7/19 (37%)
		C2H2 Zn finger	300..320	CDD:275368	6/20 (30%)
		C2H2 Zn finger	330..349	CDD:275368	3/18 (17%)
		C2H2 Zn finger	357..377	CDD:275368	8/19 (42%)
		C2H2 Zn finger	387..408	CDD:275368	8/21 (38%)
CG4424	NP_650859.3	zf-AD	10..92	CDD:285071
		C2H2 Zn finger	189..209	CDD:275368	7/19 (37%)
		DUF45	<204..281	CDD:302795	24/79 (30%)
		COG5048	210..>345	CDD:227381	39/123 (32%)
		C2H2 Zn finger	217..237	CDD:275368	6/20 (30%)
		C2H2 Zn finger	245..265	CDD:275368	4/21 (19%)
		zf-H2C2_2	257..282	CDD:290200	10/24 (42%)
		C2H2 Zn finger	273..293	CDD:275368	8/19 (42%)
		zf-H2C2_2	286..310	CDD:290200	11/25 (44%)
		C2H2 Zn finger	301..320	CDD:275368	7/18 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100