DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Plzf and Zfp143

DIOPT Version :9

Sequence 1:	NP_001285862.1	Gene:	Plzf / 34622	FlyBaseID:	FBgn0032401	Length:	469	Species:	Drosophila melanogaster
Sequence 2:	NP_001012169.2	Gene:	Zfp143 / 361627	RGDID:	1305662	Length:	638	Species:	Rattus norvegicus

Alignment Length:	275	Identity:	78/275 - (28%)
Similarity:	112/275 - (40%)	Gaps:	46/275 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   154 DPEKKAEAVFENRQSYFKLKNPRAVKSSSKVNYC--IGCDFKCYQVQKMIEHMGSCEPSHLICSL 216
            :.|||.:.|.   |.:.....|::.:|..|...|  .||. |.|..           ..||
  Rat   209 EQEKKMQIVL---QGHATRVTPKSQQSGEKAFRCKYDGCG-KLYTT-----------AHHL---- 254

  Fly   217 CEVGFLDWREYDTHLRRHSGDLRKPFFCLQ--CGIRFNTRAALLVHQPKHSTETPHIC--PHCGK 277
                       ..|.|.|:||  :|:.|..  ||..|.|...|..|...|:.|.|:.|  .:|.|
  Rat   255 -----------KVHERSHTGD--RPYQCEHSGCGKAFATGYGLKSHFRTHTGEKPYRCSEDNCTK 306

  Fly   278 GFKWKQGLSNHILVHNPEKQMLCDV--CGYSTTHMKALKSHKLLHTGEF-FACTVSGCKHRANRK 339
            .||....|..||..|..|:...|.:  ||.|.|.....|.|...||||. :.||..||.......
  Rat   307 SFKTSGDLQKHIRTHTGERPFKCPIEGCGRSFTTSNIRKVHIRTHTGERPYYCTEPGCGRAFASA 371

  Fly   340 ENLKLHIETHKQGRDFICEVCGC--KFSQSKNLKRHALKHTENGPNRYKCQLCGFSSHRSDKMKE 402
            .|.|.|:..|...:.::|.|.||  :|::..:|.:|.:.||.:.|  |.|..||.:..:...:..
  Rat   372 TNYKNHVRIHTGEKPYVCTVPGCDKRFTEYSSLYKHHVVHTHSKP--YNCNHCGKTYKQISTLAM 434

  Fly   403 HVQRVHTE-KPVQLE 416
            |.:..|.: :|::.|
  Rat   435 HKRTAHNDTEPIEEE 449

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Plzf	NP_001285862.1	COG5048	<193..403	CDD:227381	63/218 (29%)
		C2H2 Zn finger	214..234	CDD:275368	2/19 (11%)
		C2H2 Zn finger	244..264	CDD:275368	7/21 (33%)
		C2H2 Zn finger	272..292	CDD:275368	8/21 (38%)
		C2H2 Zn finger	300..320	CDD:275368	7/21 (33%)
		C2H2 Zn finger	330..349	CDD:275368	5/18 (28%)
		C2H2 Zn finger	357..377	CDD:275368	7/21 (33%)
		C2H2 Zn finger	387..408	CDD:275368	4/20 (20%)
Zfp143	NP_001012169.2	SFP1	<207..292	CDD:227516	28/114 (25%)
		C2H2 Zn finger	239..261	CDD:275368	9/48 (19%)
		COG5048	<251..424	CDD:227381	60/191 (31%)
		C2H2 Zn finger	269..291	CDD:275368	7/21 (33%)
		C2H2 Zn finger	299..321	CDD:275368	8/21 (38%)
		C2H2 Zn finger	329..351	CDD:275368	7/21 (33%)
		C2H2 Zn finger	359..381	CDD:275368	7/21 (33%)
		C2H2 Zn finger	389..411	CDD:275368	7/21 (33%)
		C2H2 Zn finger	419..438	CDD:275368	4/18 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000