DRSC/TRiP Functional Genomics Resources

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Protein Alignment Plzf and Bcl6b

DIOPT Version :9

Sequence 1:NP_001285862.1 Gene:Plzf / 34622 FlyBaseID:FBgn0032401 Length:469 Species:Drosophila melanogaster
Sequence 2:NP_001101749.1 Gene:Bcl6b / 360551 RGDID:1563179 Length:472 Species:Rattus norvegicus


Alignment Length:472 Identity:109/472 - (23%)
Similarity:146/472 - (30%) Gaps:174/472 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly    19 SKVSNYLNNQRRTGQFCDLLLELDSDDSLSLSVHFCVLAAQSQFINSNQKQQQFSIHN------- 76
            |.|.:.||..|..|...|:.|.:...   .|..|..||.|.|.|.        :||..       
  Rat    22 SDVLSNLNELRLRGILTDVTLLVGGQ---PLRAHKAVLIACSGFF--------YSIFRGRAGVGV 75

  Fly    77 -----PLKITIRNFSCTQCLHTIVDFFYEDLVSVSKEHELHFRELAQILAVTELLNLYQL----- 131
                 |.....|.|:      .::||.|...:.:|.      .....:||....|.:..:     
  Rat    76 DVLSLPGGPEARGFA------PLLDFMYTSRLRLSP------ATAPAVLAAATYLQMEHVVQACH 128

  Fly   132 -------QPLG--------EAKEATEIPAPG-----EAQP-----------------NPDPE--- 156
                   :|||        |......:|.||     |..|                 :|||:   
  Rat   129 RFIQASYEPLGISLRPMEAEPPRPPTVPPPGSPRRSEGHPDPPTESRSCSQGSPSPASPDPKACN 193

  Fly   157 -KKAEAVFENRQS---------------------------------------------------- 168
             ||.:.:..|.||                                                    
  Rat   194 WKKYKFIVLNSQSSQAGSLAGESSGQPCPQARLPSGDEACSSSSSSSSEEGATPGLQSRLSLATT 258

  Fly   169 --YFK---------LKNPRAVKSSSKV-----NYCIGCDFKCYQVQKMIEHMGSC---------- 207
              .||         |..|.|.::|.:.     :.|:.|. .|       |.:..|          
  Rat   259 TARFKCGALANNSYLFTPPAQETSKQAHPPPGSECLSCQ-NC-------EAVAGCSSGIEPLAPG 315

  Fly   208 -EPSHLICSLCEVGFLDWREYDTHLRRHSGDLRKPFFCLQCGIRFNTRAALLVHQPKHSTETPHI 271
             |.....|.||...|.......:|...|:|:  ||:.|..||.|||..|.|..|...||.|.|:.
  Rat   316 DEDKPYKCQLCRSAFRYKGNLASHRTVHTGE--KPYRCSVCGARFNRPANLKTHSRIHSGEKPYK 378

  Fly   272 CPHCGKGFKWKQGLSNHILVHNPEKQMLCDVCGYSTTHMKALKSHKLLHTGEF-FACTVSGCKHR 335
            |..||..|.....|..|:|:|..||...|..||....|::.||||..:||||. :.|...|...|
  Rat   379 CETCGSRFVQVAHLRAHVLIHTGEKPYPCPTCGTRFRHLQTLKSHVRIHTGEKPYHCDPCGLHFR 443

  Fly   336 ANRKENLKLHIETHKQG 352
              .|..|:||:. .|.|
  Rat   444 --HKSQLRLHLR-QKHG 457

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PlzfNP_001285862.1 COG5048 <193..403 CDD:227381 57/172 (33%)
C2H2 Zn finger 214..234 CDD:275368 5/19 (26%)
C2H2 Zn finger 244..264 CDD:275368 9/19 (47%)
C2H2 Zn finger 272..292 CDD:275368 7/19 (37%)
C2H2 Zn finger 300..320 CDD:275368 8/19 (42%)
C2H2 Zn finger 330..349 CDD:275368 6/18 (33%)
C2H2 Zn finger 357..377 CDD:275368
C2H2 Zn finger 387..408 CDD:275368
Bcl6bNP_001101749.1 BTB 28..132 CDD:279045 25/126 (20%)
BTB 39..131 CDD:197585 21/114 (18%)
C2H2 Zn finger 323..343 CDD:275368 5/19 (26%)
zf-H2C2_2 335..360 CDD:290200 10/26 (38%)
C2H2 Zn finger 351..371 CDD:275368 9/19 (47%)
zf-H2C2_2 363..388 CDD:290200 10/24 (42%)
C2H2 Zn finger 379..399 CDD:275368 7/19 (37%)
zf-H2C2_2 391..416 CDD:290200 9/24 (38%)
C2H2 Zn finger 407..427 CDD:275368 8/19 (42%)
zf-H2C2_2 420..444 CDD:290200 11/25 (44%)
C2H2 Zn finger 435..453 CDD:275368 7/19 (37%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

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