DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Plzf and ZBTB41

DIOPT Version :9

Sequence 1:NP_001285862.1 Gene:Plzf / 34622 FlyBaseID:FBgn0032401 Length:469 Species:Drosophila melanogaster
Sequence 2:NP_919290.2 Gene:ZBTB41 / 360023 HGNCID:24819 Length:909 Species:Homo sapiens


Alignment Length:467 Identity:122/467 - (26%)
Similarity:187/467 - (40%) Gaps:132/467 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly     3 HSQ-TMQSIP--TLHQPLHSKVSNYLNNQRRTGQFCDLLLELDSDDSLSLSVHFCVLAAQSQFIN 64
            ||: |.:|.|  ||:: |..::||  |:|.:   ||              |.|||...:....:.
Human   183 HSELTEKSSPEETLNE-LTGRLSN--NHQCK---FC--------------SRHFCYKKSLENHLA 227

  Fly    65 SNQKQQQFSIHNPLKITIRNFS---------CTQCLHTIVDFFYE-------------------- 100
            ...:.......:.||:..|:||         |........|...|                    
Human   228 KTHRSLLLGKKHGLKMLERSFSARRSKRNRKCPVKFDDTSDDEQESGDGSDNLNQENFDKEKSDR 292

  Fly   101 -DLVSVSKEHELHFRELAQILAVTELLNLY---QLQPLGEAKEATEIPAPGEAQPNPDPEKKAEA 161
             |......|:.....||.:     |:.:.|   :.|...:..:|.|.|..|::..|.. |.....
Human   293 NDSEDPGSEYNAEEDELEE-----EMSDEYSDIEEQSEKDHNDAEEEPEAGDSVGNVH-EGLTPV 351

  Fly   162 VFENRQSYFKLKNPRAVKSSSKVNYCIGCDFKCYQVQKMIEHMGSCEPSHLICSLCEVGFLDWRE 226
            |.:|              |:.|:..|..||       |..:.:|                    :
Human   352 VIQN--------------SNKKILQCPKCD-------KTFDRIG--------------------K 375

  Fly   227 YDTHLRRHSGDLRKPFFCLQCGIRFNTRAALLVHQPKHSTET-----PHICPHCGKGFKWKQGLS 286
            |::|.|.|:|:  |||.|..|..|::|::.|.||:.|||.||     .|.||:|.|....|:.|:
Human   376 YESHTRVHTGE--KPFECDICHQRYSTKSNLTVHRKKHSNETEFHKKEHKCPYCNKLHASKKTLA 438

  Fly   287 NHILVHNPE-------------KQMLCDVCGYSTTHMKALKSHKLLHTGEF-FACTVSGC-KHRA 336
            .|:...:||             :...||:|..|.|....|:.|.:||:.:. |.||.  | :|..
Human   439 KHVKRFHPENAQEFISIKKTKSESWKCDICKKSFTRRPHLEEHMILHSQDKPFKCTY--CEEHFK 501

  Fly   337 NRKENLKLHIETHKQGRDFICEVCGCKFSQSKNLKRHALKHTENGPNRYKCQLCGFSSHRSDKMK 401
            :|...|| |.|....| .|.|::||.:|:.:.||||| ::.|..|..::.|.:||.|......:|
Human   502 SRFARLK-HQEKFHLG-PFPCDICGRQFNDTGNLKRH-IECTHGGKRKWTCFICGKSVRERTTLK 563

  Fly   402 EHVQRVHT-EKP 412
            ||: |:|: |||
Human   564 EHL-RIHSGEKP 574

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PlzfNP_001285862.1 COG5048 <193..403 CDD:227381 69/229 (30%)
C2H2 Zn finger 214..234 CDD:275368 3/19 (16%)
C2H2 Zn finger 244..264 CDD:275368 7/19 (37%)
C2H2 Zn finger 272..292 CDD:275368 7/19 (37%)
C2H2 Zn finger 300..320 CDD:275368 7/19 (37%)
C2H2 Zn finger 330..349 CDD:275368 7/19 (37%)
C2H2 Zn finger 357..377 CDD:275368 9/19 (47%)
C2H2 Zn finger 387..408 CDD:275368 8/20 (40%)
ZBTB41NP_919290.2 BTB_POZ_ZBTB41 66..179 CDD:349535
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 252..344 14/96 (15%)
C2H2 Zn finger 363..383 CDD:275368 8/46 (17%)
C2H2 Zn finger 391..411 CDD:275368 7/19 (37%)
C2H2 Zn finger 424..442 CDD:275368 7/17 (41%)
C2H2 Zn finger 465..485 CDD:275368 7/19 (37%)
C2H2 Zn finger 493..510 CDD:275368 7/19 (37%)
C2H2 Zn finger 520..541 CDD:275368 9/21 (43%)
C2H2 Zn finger 549..569 CDD:275368 8/20 (40%)
C2H2 Zn finger 577..597 CDD:275368
zf-C2H2 603..625 CDD:395048
C2H2 Zn finger 605..625 CDD:275368
C2H2 Zn finger 633..651 CDD:275368
C2H2 Zn finger 670..687 CDD:275368
C2H2 Zn finger 698..718 CDD:275368
C2H2 Zn finger 726..743 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

Return to query results.
Submit another query.