DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Plzf and CG30431

DIOPT Version :9

Sequence 1:	NP_001285862.1	Gene:	Plzf / 34622	FlyBaseID:	FBgn0032401	Length:	469	Species:	Drosophila melanogaster
Sequence 2:	NP_610211.1	Gene:	CG30431 / 35549	FlyBaseID:	FBgn0050431	Length:	418	Species:	Drosophila melanogaster

Alignment Length:	303	Identity:	79/303 - (26%)
Similarity:	107/303 - (35%)	Gaps:	72/303 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    92 HTIVDFFYEDLVSVSKEHELHFRELAQILAVTELLNLYQLQPLGEAKEATEIPAPGEAQPNPDP- 155
            |.|..::...:.|.|.....|..|.|::.||                   |.|.|.|:...|.|
  Fly   153 HDIPSYWESSVDSGSLNTPHHQPETAELFAV-------------------EPPTPPESSEEPAPD 198

  Fly   156 --EKKAEAVFENRQSYFKLKNPRAVKSSSKV-----NYCIGCDFKCYQVQKMIEHM----GSCEP 209
              ||........||...|   |:..|:|..|     :.|..|:.|..:..::..||    |..|.
  Fly   199 AAEKPKMRRARPRQDNVK---PKERKASGAVHPRSLHPCPECEKKFTRNFQLKLHMTAVHGMGEM 260

  Fly   210 SHLICSLCEVGFLDWREYDTHLRR-HSGDLRKPFFCLQCGIRFNTRAALLVHQPKHSTET-PHI- 271
            .:. |..|...|........|::. ||.:  :||.|..|..||..|..||.|...|:.|. |.|
  Fly   261 RYQ-CEECRKNFASRHSLRYHVKSVHSTE--RPFGCQHCDRRFILRTQLLSHLRTHTGEAKPRIF 322

  Fly   272 -CPHCGKGFKWKQGLSNHILVHNP--EKQMLCDVCGYSTTHMKALKSHKLLHTGEFFACTVSGCK 333
             |..|.|.:..|..|..|:..|||  |:...||.|..:......|.||.|:||||
  Fly   323 ECQRCSKSWPTKSDLRTHMRSHNPNMERPFKCDRCSKAFFTRGHLNSHLLVHTGE---------- 377

  Fly   334 HRANRKENLKLHIETHKQGRDFICEVCGCKFSQSKNLKRHALK 376
                               :.|.||.|...:....||..|.::
  Fly   378 -------------------KPFACEYCDKCYQSVGNLNNHMVR 401

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Plzf	NP_001285862.1	COG5048	<193..403	CDD:227381	53/194 (27%)
		C2H2 Zn finger	214..234	CDD:275368	4/20 (20%)
		C2H2 Zn finger	244..264	CDD:275368	8/19 (42%)
		C2H2 Zn finger	272..292	CDD:275368	6/19 (32%)
		C2H2 Zn finger	300..320	CDD:275368	7/19 (37%)
		C2H2 Zn finger	330..349	CDD:275368	0/18 (0%)
		C2H2 Zn finger	357..377	CDD:275368	6/20 (30%)
		C2H2 Zn finger	387..408	CDD:275368
CG30431	NP_610211.1	zf-AD	11..82	CDD:285071
		C2H2 Zn finger	234..255	CDD:275368	5/20 (25%)
		C2H2 Zn finger	264..285	CDD:275368	4/20 (20%)
		C2H2 Zn finger	293..313	CDD:275368	8/19 (42%)
		zf-C2H2_8	305..373	CDD:292531	23/67 (34%)
		C2H2 Zn finger	324..344	CDD:275368	6/19 (32%)
		C2H2 Zn finger	354..374	CDD:275368	7/19 (37%)
		zf-H2C2_2	366..389	CDD:290200	12/51 (24%)
		C2H2 Zn finger	382..403	CDD:275368	6/20 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45453386
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030