DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Plzf and CG9609

DIOPT Version :9

Sequence 1:	NP_001285862.1	Gene:	Plzf / 34622	FlyBaseID:	FBgn0032401	Length:	469	Species:	Drosophila melanogaster
Sequence 2:	NP_573161.1	Gene:	CG9609 / 32663	FlyBaseID:	FBgn0030787	Length:	403	Species:	Drosophila melanogaster

Alignment Length:	398	Identity:	92/398 - (23%)
Similarity:	135/398 - (33%)	Gaps:	135/398 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   134 LGEAKEATEIPAPGEAQPNPDPEKKAEAVFE-----NRQSYFKLKNPRAVKSSSKVNYCI--GCD 191
            :|.||.|..:|             |.||.|:     :|..|.        .:..|.:.|.  |||
  Fly    30 IGSAKYACSMP-------------KCEATFKRLDQLDRHEYH--------HTGIKKHACSYEGCD 73

  Fly   192 FKCYQV--------QKMIEHMGSCEPSHLICSL--CEVGFLDWREYDTHLRRHSGDLRKPFFCLQ 246
             |.|.:        :...|...|.....:.|:|  |...|:.......|: |.:.:..|.:.|.|
  Fly    74 -KTYSIVTHLKRHLRSTHERPESAAKKTVKCALEECSKMFISVSNMTRHM-RETHESPKVYPCSQ 136

  Fly   247 CGIRFNTRAALLVHQ-PKHSTETPHICPHCGKGF--------------------------KWK-- 282
            |..:|:.:..|..|: .:|:.|.|:.|..|.:||                          ||.
  Fly   137 CSAKFSQKLKLKRHEIREHTLEYPYSCSKCSRGFYQQWQCQSHEPSCKLYECPGCPLQFDKWTLY 201

  Fly   283 --------QGLSNHILVHNPEKQMLCDVCGYSTTHMKALKSH------KLLHTGE---FFACTVS 330
                    .|.:.|          .||.|..:......||.|      :...|.|   .|.|...
  Fly   202 TKHCRDSLHGKNRH----------KCDRCDSAFDKPSELKRHLEVKHKEAAQTDECATSFTCNEE 256

  Fly   331 GCKHRANRKENLKLHIETHKQGRDFICEV--CGCKFSQSKNLKRHALKHTENG------------ 381
            ||....:...||:.|:.|...||.|.|:.  ||..||.::||.||.|:..::|
  Fly   257 GCGKSYSYLRNLRQHMLTAHSGRRFECQALDCGRCFSSAQNLARHLLRDHKDGATKKELKAKKKD 321

  Fly   382 ------------PNRYKCQLCGFSSH-RSDKM------KEHVQRVHTEKPVQLELSETVDSSFPD 427
                        .:|.:.:..|.|.| |..|:      ||..:.|...:|:.|   |.:..|..|
  Fly   322 KSKTGEGGKTKSTSRKRRRDAGRSKHSRLSKLACLQLDKEDDEAVRERQPLVL---EKITQSLKD 383

  Fly   428 DFELPVIE 435
            |   ||.|
  Fly   384 D---PVEE 388

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Plzf	NP_001285862.1	COG5048	<193..403	CDD:227381	65/298 (22%)
		C2H2 Zn finger	214..234	CDD:275368	5/21 (24%)
		C2H2 Zn finger	244..264	CDD:275368	6/20 (30%)
		C2H2 Zn finger	272..292	CDD:275368	8/55 (15%)
		C2H2 Zn finger	300..320	CDD:275368	6/25 (24%)
		C2H2 Zn finger	330..349	CDD:275368	5/18 (28%)
		C2H2 Zn finger	357..377	CDD:275368	10/21 (48%)
		C2H2 Zn finger	387..408	CDD:275368	7/27 (26%)
CG9609	NP_573161.1	C2H2 Zn finger	40..59	CDD:275368	7/39 (18%)
		zf-C2H2_8	67..150	CDD:292531	20/84 (24%)
		C2H2 Zn finger	67..90	CDD:275368	6/23 (26%)
		C2H2 Zn finger	106..126	CDD:275368	4/20 (20%)
		C2H2 Zn finger	134..155	CDD:275368	6/20 (30%)
		C2H2 Zn finger	188..210	CDD:275368	2/21 (10%)
		C2H2 Zn finger	217..237	CDD:275368	6/19 (32%)
		C2H2 Zn finger	253..276	CDD:275368	7/22 (32%)
		C2H2 Zn finger	283..302	CDD:275368	8/18 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100