DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Plzf and Zbtb43

DIOPT Version :9

Sequence 1:	NP_001285862.1	Gene:	Plzf / 34622	FlyBaseID:	FBgn0032401	Length:	469	Species:	Drosophila melanogaster
Sequence 2:	NP_001012094.1	Gene:	Zbtb43 / 311872	RGDID:	1310287	Length:	503	Species:	Rattus norvegicus

Alignment Length:	190	Identity:	40/190 - (21%)
Similarity:	68/190 - (35%)	Gaps:	31/190 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   100 EDLVSVSKEHELHFRELAQILAVTELLNLYQLQPLGEAKEATEIPAPGEAQPNPDPEKKAEAVFE 164
            |:...|.|:.|:.|.|.|:.....|.::.|                 |.:......||....:..
  Rat   325 EEFQIVEKKVEVEFDEHAEGSNYDEQVDFY-----------------GSSMEEFSGEKLGGGLIG 372

  Fly   165 NRQSYFKLKNPRAVKSSSKVNYCIGCDFKCYQVQKMIEHMGSCEPSHLICSLCEVGFLDWREYDT 229
            ::|     :...|...|..:...:|       :::...|:|......|....|...|....:.|.
  Rat   373 HKQ-----ETALAAGYSENIEMVMG-------IKEEASHLGFSATDKLYPCQCGKSFTHKSQRDR 425

  Fly   230 HLRRHSGDLRKPFFCLQCGIRFNTRAALLVHQPKHSTETPHICPHCGKGFKWKQGLSNHI 289
            |:..|.|  .:|:.|..||.:|..:..|:.|...|:...|:.|..|.|.|.|:.....|:
  Rat   426 HMSMHLG--LRPYGCSVCGKKFKMKHHLVGHMKIHTGIKPYECNICAKRFMWRDSFHRHV 483

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Plzf	NP_001285862.1	COG5048	<193..403	CDD:227381	24/97 (25%)
		C2H2 Zn finger	214..234	CDD:275368	4/19 (21%)
		C2H2 Zn finger	244..264	CDD:275368	6/19 (32%)
		C2H2 Zn finger	272..292	CDD:275368	6/18 (33%)
		C2H2 Zn finger	300..320	CDD:275368
		C2H2 Zn finger	330..349	CDD:275368
		C2H2 Zn finger	357..377	CDD:275368
		C2H2 Zn finger	387..408	CDD:275368
Zbtb43	NP_001012094.1	BTB_POZ_ZBTB43	44..164	CDD:349536
		C2H2 Zn finger	412..430	CDD:275368	4/17 (24%)
		C2H2 Zn finger	438..458	CDD:275368	6/19 (32%)
		zf-H2C2_2	450..473	CDD:404364	7/22 (32%)
		C2H2 Zn finger	466..483	CDD:275368	5/16 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000