DRSC/TRiP Functional Genomics Resources

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Protein Alignment Plzf and Zbtb46

DIOPT Version :9

Sequence 1:NP_001285862.1 Gene:Plzf / 34622 FlyBaseID:FBgn0032401 Length:469 Species:Drosophila melanogaster
Sequence 2:NP_001101278.1 Gene:Zbtb46 / 311718 RGDID:1307408 Length:601 Species:Rattus norvegicus


Alignment Length:521 Identity:102/521 - (19%)
Similarity:163/521 - (31%) Gaps:179/521 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly    25 LNNQRRTGQFCDLLLELDSDDSLSLSVHFCVLAAQSQFINSNQKQQQFSIHNPLKITIRNFSCTQ 89
            ||.||:.|..||:.:.::..   ....|..||...|::..:...|.| ...:...:|..:....|
  Rat    21 LNEQRQHGVLCDVCVVVEGK---VFKAHKNVLLGSSRYFKTLYCQVQ-KTSDQATVTHLDIVTAQ 81

  Fly    90 CLHTIVDFFYEDLVSVSKEHELHFRELAQILAVTEL-----------------------LNLYQL 131
            ....|:||.|...::::..:.:.....|..|.:|::                       |:.:::
  Rat    82 GFKAIIDFMYSAHLALTSRNVIEVMSAASFLQMTDIVQACHDFIKAALDISIKSDASDELSEFEI 146

  Fly   132 -QPLGEAKEA--TEIPAPGEAQP---------NPDPEKKAEAVFENRQSYFKL-KNPRA-----V 178
             .|...:.||  :.:.|.....|         |...:....:..|...||.|. :.|:|     |
  Rat   147 GTPASNSTEALISAVMAGRSISPWLARRTSPANSSGDSAIASCHEGGSSYGKEDQEPKADGPDDV 211

  Fly   179 KSSS----KVNYCIGCDFKCYQVQKMIEHMGSCEPSH-----LICSLCEVGFLD-WREYDTHLRR 233
            .|.|    .|.|   ...:..:.|....|.|..|.|.     :..||.|.|..| |:.......|
  Rat   212 SSQSLWPGDVGY---GSLRIKEEQISPSHYGGSELSSSKDAAIQNSLSEQGSGDGWQPTGRRKNR 273

  Fly   234 HSGDLRK----------------PFFCLQCGIRFNT--------------------RAALLVHQP 262
            .:.:..:                |.|....|..|::                    ||.|..|  
  Rat   274 KNKETVRHITQQVEEDSQAGSPVPSFLPTSGWPFSSRDSNVDLTVTEASSLDSRGERAELYAH-- 336

  Fly   263 KHSTE----------TPHICPHCGKGFKWKQGLSN------------------------------ 287
             |..|          .|.:.|...:.......::|                              
  Rat   337 -HIDEGLLGGETSYLGPPLTPEKEEALHQATAVANLRAALMSKNSLLSLKADVLGDDGSLLFEYL 400

  Fly   288 ----HILVHNP----EKQMLCDVCGYSTTHMKALKSHKLLHTGEFFACTVSGCKHRANRKENLKL 344
                |.|..|.    .|:..|..|.:|..|...||.|...||||                     
  Rat   401 PKGAHSLSLNEFTVIRKKFKCPYCSFSAMHQCILKRHMRSHTGE--------------------- 444

  Fly   345 HIETHKQGRDFICEVCGCKFSQSKNLKRHALKHTENGPNRYKCQLCG--FSSHRSDKMKEHVQRV 407
                    |.:.||:||.||::.:::|||.|.|:::  .:|.|::|.  |.|..|..:| |..|.
  Rat   445 --------RPYPCEICGKKFTRREHMKRHTLVHSKD--KKYVCKVCSRVFMSAASVGIK-HGSRR 498

  Fly   408 H 408
            |
  Rat   499 H 499

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PlzfNP_001285862.1 COG5048 <193..403 CDD:227381 59/301 (20%)
C2H2 Zn finger 214..234 CDD:275368 6/20 (30%)
C2H2 Zn finger 244..264 CDD:275368 6/39 (15%)
C2H2 Zn finger 272..292 CDD:275368 4/53 (8%)
C2H2 Zn finger 300..320 CDD:275368 7/19 (37%)
C2H2 Zn finger 330..349 CDD:275368 0/18 (0%)
C2H2 Zn finger 357..377 CDD:275368 10/19 (53%)
C2H2 Zn finger 387..408 CDD:275368 8/22 (36%)
Zbtb46NP_001101278.1 BTB 21..126 CDD:279045 22/108 (20%)
BTB 32..126 CDD:197585 16/97 (16%)
COG5048 <362..>487 CDD:227381 32/155 (21%)
C2H2 Zn finger 421..441 CDD:275368 7/19 (37%)
zf-H2C2_2 434..458 CDD:290200 14/52 (27%)
C2H2 Zn finger 449..469 CDD:275368 10/19 (53%)
zf-H2C2_2 461..484 CDD:290200 8/24 (33%)
C2H2 Zn finger 477..499 CDD:275368 8/22 (36%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

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