DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Plzf and CG11398

DIOPT Version :9

Sequence 1:	NP_001285862.1	Gene:	Plzf / 34622	FlyBaseID:	FBgn0032401	Length:	469	Species:	Drosophila melanogaster
Sequence 2:	NP_001259122.2	Gene:	CG11398 / 31070	FlyBaseID:	FBgn0040366	Length:	329	Species:	Drosophila melanogaster

Alignment Length:	304	Identity:	72/304 - (23%)
Similarity:	123/304 - (40%)	Gaps:	51/304 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   192 FKCYQVQKMIEHMGSCEPSHLICSLCEVGFLDWREYDTHLRRHSGDLRKPFFCLQCGIRFNTRAA 256
            :|..::..::.|  :.|...|..:..|:.|.:..|...|.:..|    ..|.|.:|...|.||..
  Fly     6 YKEAEILALLPH--TYEDEELSLNTEELQFEELNERSQHQQGGS----PSFVCRRCPALFLTREE 64

  Fly   257 LLVHQPKH----STETP---HICPHCGKGFKWKQGLSNHILVHNPEKQMLCDVC-------GYST 307
            |..|:|.|    ..:||   |.|..||:.|:....|.:|:..||..:...|..|       ....
  Fly    65 LAAHRPTHRYQGGQQTPASEHACDACGRVFQKHNALVDHMNAHNDVRNYPCPECPARFVQRSNRE 129

  Fly   308 THMKALKSHKLLHTGEFFACTVSGCKHRANRKENLKLHIET-HKQGRDFICEVCGCKFSQSKNLK 371
            .|:|.:.....||     :|...|||.|..::.....|::| |:..|:.:|:.|..:||...|.:
  Fly   130 CHLKNVHRKVYLH-----SCPEPGCKKRFQQRRECDQHVKTVHQNERNLVCDTCSARFSHPVNYR 189

  Fly   372 RHALKHTENGPNRYKCQLCGFSSHRSDKMKEHVQRVHT--------------EKPVQLELSETVD 422
            :|...|  .....|.|.:||....|.:....|: .||:              .:..|| :...:.
  Fly   190 KHLASH--GSAKSYGCPICGKLFGRPENRDVHL-FVHSICKAYICSVCGADYMRRNQL-IRHGLA 250

  Fly   423 SSFPDDFELPVIETSPKKKPK-SVKSKTIRNV---NPDKRLKTL 462
            |...:|   |::...|:..|. :.|:::.|:.   :.|:.|:.|
  Fly   251 SGHHND---PIVRQKPQFSPALAAKNRSQRSAIDESQDEELQWL 291

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Plzf	NP_001285862.1	COG5048	<193..403	CDD:227381	57/224 (25%)
		C2H2 Zn finger	214..234	CDD:275368	4/19 (21%)
		C2H2 Zn finger	244..264	CDD:275368	8/19 (42%)
		C2H2 Zn finger	272..292	CDD:275368	6/19 (32%)
		C2H2 Zn finger	300..320	CDD:275368	4/26 (15%)
		C2H2 Zn finger	330..349	CDD:275368	6/19 (32%)
		C2H2 Zn finger	357..377	CDD:275368	6/19 (32%)
		C2H2 Zn finger	387..408	CDD:275368	5/20 (25%)
CG11398	NP_001259122.2	C2H2 Zn finger	52..72	CDD:275368	8/19 (42%)
		C2H2 Zn finger	87..107	CDD:275368	6/19 (32%)
		C2H2 Zn finger	115..136	CDD:275368	4/20 (20%)
		C2H2 Zn finger	144..165	CDD:275368	6/20 (30%)
		C2H2 Zn finger	175..195	CDD:275368	6/19 (32%)
		C2H2 Zn finger	203..223	CDD:275368	5/20 (25%)
		C2H2 Zn finger	231..247	CDD:275368	2/16 (13%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45446601
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030