DRSC/TRiP Functional Genomics Resources

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Protein Alignment Plzf and BCL6B

DIOPT Version :9

Sequence 1:NP_001285862.1 Gene:Plzf / 34622 FlyBaseID:FBgn0032401 Length:469 Species:Drosophila melanogaster
Sequence 2:NP_862827.2 Gene:BCL6B / 255877 HGNCID:1002 Length:479 Species:Homo sapiens


Alignment Length:250 Identity:73/250 - (29%)
Similarity:98/250 - (39%) Gaps:53/250 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly   136 EAKEATEIPAPGEAQPNPDPEKKAEAVFENRQSYFKLKNPRAVK--SSSKVNYCIGCDFKCYQVQ 198
            :|::.:..|:. .|:|.|..|            :|..:|..||.  ||...:...|.:.|.|:  
Human   280 QAQDTSGSPSE-RARPLPGSE------------FFSCQNCEAVAGCSSGLDSLVPGDEDKPYK-- 329

  Fly   199 KMIEHMGSCEPSHLICSLCEVGFLDWREYDTHLRRHSGDLRKPFFCLQCGIRFNTRAALLVHQPK 263
                           |.||...|.......:|...|:|:  ||:.|..||.|||..|.|..|...
Human   330 ---------------CQLCRSSFRYKGNLASHRTVHTGE--KPYHCSICGARFNRPANLKTHSRI 377

  Fly   264 HSTETPHICPHCGKGFKWKQGLSNHILVHNPEKQMLCDVCGYSTTHMKALKSHKLLHTGEF-FAC 327
            ||.|.|:.|..||..|.....|..|:|:|..||...|..||....|::.||||..:||||. :.|
Human   378 HSGEKPYKCETCGSRFVQVAHLRAHVLIHTGEKPYPCPTCGTRFRHLQTLKSHVRIHTGEKPYHC 442

  Fly   328 TVSGCKHRANRKENLKLHIETHKQGRDFICEVCGCKFSQSKNLKRHALKHTENGP 382
            ...|...|  .|..|:||:..              |...:.|.|.|  .|...||
Human   443 DPCGLHFR--HKSQLRLHLRQ--------------KHGAATNTKVH--YHILGGP 479

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PlzfNP_001285862.1 COG5048 <193..403 CDD:227381 59/190 (31%)
C2H2 Zn finger 214..234 CDD:275368 5/19 (26%)
C2H2 Zn finger 244..264 CDD:275368 9/19 (47%)
C2H2 Zn finger 272..292 CDD:275368 7/19 (37%)
C2H2 Zn finger 300..320 CDD:275368 8/19 (42%)
C2H2 Zn finger 330..349 CDD:275368 6/18 (33%)
C2H2 Zn finger 357..377 CDD:275368 4/19 (21%)
C2H2 Zn finger 387..408 CDD:275368
BCL6BNP_862827.2 BTB_POZ 19..132 CDD:365784
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 143..190
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 210..259
C2H2 Zn finger 330..350 CDD:275368 5/19 (26%)
COG5048 354..>411 CDD:227381 24/56 (43%)
C2H2 Zn finger 358..378 CDD:275368 9/19 (47%)
zf-H2C2_2 370..395 CDD:372612 10/24 (42%)
C2H2 Zn finger 386..406 CDD:275368 7/19 (37%)
zf-C2H2 412..434 CDD:333835 8/21 (38%)
C2H2 Zn finger 414..434 CDD:275368 8/19 (42%)
zf-H2C2_2 427..451 CDD:372612 11/25 (44%)
C2H2 Zn finger 442..460 CDD:275368 7/19 (37%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

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