DRSC/TRiP Functional Genomics Resources

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Protein Alignment Plzf and ZBTB38

DIOPT Version :9

Sequence 1:NP_001285862.1 Gene:Plzf / 34622 FlyBaseID:FBgn0032401 Length:469 Species:Drosophila melanogaster
Sequence 2:XP_005247313.1 Gene:ZBTB38 / 253461 HGNCID:26636 Length:1196 Species:Homo sapiens


Alignment Length:343 Identity:79/343 - (23%)
Similarity:127/343 - (37%) Gaps:73/343 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly   129 YQLQPLGEAKEATEIPAPGEAQPNPDPEK----------KAEAVFENRQ-------------SYF 170
            ||:|         |.|.|....|.|..:.          :...||::..             :|.
Human   869 YQMQ---------EEPLPQGNDPEPSGDSPLGLCQSECMEMSEVFDDASDQDSTDKPWRPYYNYK 924

  Fly   171 KLKNPRAVKSSSKVNY------------C-----IGCDFKCYQVQKMIEHMGSCEPSHLICSLCE 218
            ..|..|.:|...|||:            |     :.|........|..|...:.|...|.|.||:
Human   925 PKKKSRQLKKMRKVNWRKEHGNRSPSHKCKYPAELDCAVGKAPQDKPFEEEETKEMPKLQCELCD 989

  Fly   219 ----VGFLDWREYDTHLRRHSGDLRKPFFCLQCGIRFNTRAALLVHQPKHSTETPHICPHCGKGF 279
                ||..:......||      ..:|:.|..|..:|.:.:.|.:|...|:.|.|:.|..||:.|
Human   990 GDKAVGAGNQGRPHRHL------TSRPYACELCAKQFQSPSTLKMHMRCHTGEKPYQCKTCGRCF 1048

  Fly   280 KWKQGLSNHILVHNPEKQMLCDVCGYSTTHMKALKSHKLLHTGE-FFACTVSGCKHR----ANRK 339
            ..:..|..|..:|...|:.:|..|..:.|..:.||.|:.:|||| .:.|..  |..|    :.::
Human  1049 SVQGNLQKHERIHLGLKEFVCQYCNKAFTLNETLKIHERIHTGEKRYHCQF--CFQRFLYLSTKR 1111

  Fly   340 ENLKLHIETHKQGRDFICEVCG--CKFSQSKNLKRHALKHTENGPNRYKCQLCGFSSHRSDKMKE 402
            .:.:.||..| .|:.:.|..|.  ||.:.:  |..|..||....|::.  :..|...|.:....|
Human  1112 NHEQRHIREH-NGKGYACFQCPKICKTAAA--LGMHQKKHLFKSPSQQ--EKIGDVCHENSNPLE 1171

  Fly   403 HVQRVHTEKPVQLELSET 420
            :...:.:|...|.:..:|
Human  1172 NQHFIGSEDNDQKDNIQT 1189

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PlzfNP_001285862.1 COG5048 <193..403 CDD:227381 56/220 (25%)
C2H2 Zn finger 214..234 CDD:275368 7/23 (30%)
C2H2 Zn finger 244..264 CDD:275368 5/19 (26%)
C2H2 Zn finger 272..292 CDD:275368 6/19 (32%)
C2H2 Zn finger 300..320 CDD:275368 6/19 (32%)
C2H2 Zn finger 330..349 CDD:275368 4/22 (18%)
C2H2 Zn finger 357..377 CDD:275368 6/21 (29%)
C2H2 Zn finger 387..408 CDD:275368 3/20 (15%)
ZBTB38XP_005247313.1 BTB 24..123 CDD:279045
BTB 35..131 CDD:197585
C2H2 Zn finger 345..365 CDD:275368
C2H2 Zn finger 374..393 CDD:275368
C2H2 Zn finger 463..483 CDD:275368
C2H2 Zn finger 491..511 CDD:275368
C2H2 Zn finger 519..537 CDD:275368
C2H2 Zn finger 1013..1033 CDD:275368 5/19 (26%)
zf-H2C2_2 1026..1049 CDD:290200 8/22 (36%)
zf-C2H2 1039..1061 CDD:278523 6/21 (29%)
C2H2 Zn finger 1041..1061 CDD:275368 6/19 (32%)
zf-H2C2_2 1053..1077 CDD:290200 6/23 (26%)
C2H2 Zn finger 1069..1089 CDD:275368 6/19 (32%)
zf-H2C2_2 1082..1106 CDD:290200 10/25 (40%)
C2H2 Zn finger 1097..1121 CDD:275368 5/25 (20%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

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