Protein Alignment Plzf and szy-5

DIOPT Version :10

• Sequence 1: NP_609540.2
• Gene: Plzf / 34622
• FlyBaseID: FBgn0032401
• Length: 469
• Species: Drosophila melanogaster
• Sequence 2: NP_491745.2
• Gene: szy-5 / 172281
• WormBaseID: WBGene00016154
• Length: 603
• Species: Caenorhabditis elegans
• Alignment Length: 540
• Identity: 103/540 - (19%)
• Similarity: 186/540 - (34%)
• Gaps: 169/540 - (31%)

  Fly    14 HQPLHSKVSNYLNNQRRTGQ---FCDLLLELDSDDSLSLSVH-------------FCVLAAQSQF 62
            |....||::.::  ::.||:   .|. :..:....:.:|..|             ||.    ::|
 Worm    79 HIKYPSKITEHI--RKHTGEKPNVCS-ICNISFSQAHTLKTHMQQHAHEKPYKCSFCT----AEF 136

  Fly    63 IN---SNQKQQQFSIHNP-------------------LKITIRNFSCT--QCLHTIVDFFYEDLV 103
            :|   .|:.::| .:|:|                   .:.||:...|.  :|........||:..
 Worm   137 LNVYEKNEHEEQ-HMHHPNHGETMEENNATTSQFIQVAEPTIQAEPCQIYECSEMCGFQSYEEAE 200

  Fly   104 SVSKEHELHFRELAQILAVTELLN--------LYQLQPLGEA-KEATEIP--------------- 144
            .|......|:::..|...:.:..|        .|:.|.:.:. .|..|.|
 Worm   201 VVEHMTVTHYQQTVQNGLILQDFNGEPEPIYEFYEEQYVQQVPTEIEETPTIKQQSIPYENLHFE 265

  Fly   145 ----APGEAQPNPDPEKKAEAVFENRQSYFKLKNPRAVKSSSKVNYCIGCDFKCY----QVQKMI 201
                |||.::|:.....:.|.:::. :....:.|.:::|...:     ..|...|    .:::.:
 Worm   266 HVEAAPGPSEPHLQVVAEGEILYDG-EEIVDISNGKSLKEEIQ-----NGDANIYGMIQDLEEEV 324

  Fly   202 EHMG-----------------------SCEPSHLICS-----LCEVGFLDWREYDTHLRRHSGDL 238
            |.:|                       |....|...:     :.:...|:..|...||::....:
 Worm   325 EDIGNEDEERERVRIMVNPNPPKRGTKSLRDHHEATAATMEMIVDASILELAEPSRHLKQGYPPI 389

  Fly   239 RKPFFCLQCGIRFNT--RAALL--------------VHQPKHSTE-TPHICPHCGKGFKWKQGLS 286
            .|         |.||  ||..|              ...|.|..: |.|.|.:||:..|:...:.
 Worm   390 SK---------RKNTGKRAENLDWIIDAVAKGVDVSEASPHHRKKPTLHKCEYCGRVDKYPSKIR 445

  Fly   287 NHILVHNPEKQMLCDVCGYSTTHMKALKSHKLLHTGEF-FACTVSGCKHRANRKENLKLHIE-TH 349
            .|:..|..||...|::||.:.:....::.|...|..:. :.|.|.|||.|......||:|:| .|
 Worm   446 AHMRTHTGEKPFKCEICGMAFSQKTPMRLHLRRHFDQKPYECDVDGCKERFVSGAILKMHVEKKH 510

  Fly   350 KQGRDFIC-EVCGCKFSQSKNLKRHALKHTENGPNRYKCQLCGFSSHRSDKMKEHVQRVHTEKPV 413
            ...:.::| ..||..||.:.|.|.|          ..||:            :.:|..|..|:.
 Worm   511 LNKKKYVCSRGCGRVFSSAYNQKHH----------EKKCE------------QTYVTWVEGEQQ- 552

  Fly   414 QLELSETVDSS---FPDDFE 430
            .:|..|..:.|   :|||.|
 Worm   553 SVESGEEDEESNGEYPDDDE 572

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Plzf	NP_609540.2	COG5048	<193..403	CDD:227381	54/261 (21%)
		C2H2 Zn finger	214..234	CDD:275368	4/24 (17%)
		C2H2 Zn finger	244..264	CDD:275368	7/35 (20%)
		C2H2 Zn finger	272..292	CDD:275368	5/19 (26%)
		C2H2 Zn finger	300..320	CDD:275368	4/19 (21%)
		C2H2 Zn finger	330..349	CDD:275368	8/19 (42%)
		C2H2 Zn finger	357..377	CDD:275368	8/20 (40%)
		C2H2 Zn finger	387..408	CDD:275368	2/20 (10%)
szy-5	NP_491745.2	C2H2 Zn finger	73..93	CDD:275368	3/15 (20%)
		C2H2 Zn finger	101..121	CDD:275368	3/20 (15%)
		C2H2 Zn finger	129..149	CDD:275368	6/24 (25%)
		C2H2 Zn finger	431..451	CDD:275368	5/19 (26%)
		zf-H2C2_2	447..468	CDD:463886	7/20 (35%)
		C2H2 Zn finger	459..479	CDD:275368	4/19 (21%)
		C2H2 Zn finger	487..506	CDD:275368	8/18 (44%)