DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Plzf and zbtb47

DIOPT Version :9

Sequence 1:	NP_001285862.1	Gene:	Plzf / 34622	FlyBaseID:	FBgn0032401	Length:	469	Species:	Drosophila melanogaster
Sequence 2:	XP_004915642.1	Gene:	zbtb47 / 100489594	XenbaseID:	XB-GENE-992955	Length:	733	Species:	Xenopus tropicalis

Alignment Length:	261	Identity:	80/261 - (30%)
Similarity:	115/261 - (44%)	Gaps:	22/261 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   155 PEKKAEAVFENRQSYFKLKNPRAVKSSSKVNYCIGCDFKC-----YQVQKMIEHMGSCEPSHLIC 214
            |.||...||.||  ::..|:.....|..::     || ||     .:.:.|:.|...|| .::.|
Frog   405 PCKKCPRVFNNR--WYLEKHMNVTHSRMRI-----CD-KCGKRFLLESELMLHHQTDCE-KNIQC 460

  Fly   215 SLCEVGFLDWREYDTHLRRHSGDLRKPFFCLQCGIRFNTRAALLVHQPKHSTETPHICPHCGKGF 279
            ..|...|........|.:...|...|.|.|..|..:|.|.|.:..|...|:.:.|..|..|||.|
Frog   461 LTCGKTFKKLWSLHEHNKIVHGYAEKKFSCDICEKKFYTMAHVRKHLVAHTKDMPFTCETCGKSF 525

  Fly   280 KWKQGLSNHILVHNPEKQMLCDVCGYSTTHMKALKSHKLLHTG-EFFACTVSGCKHRANRKENLK 343
            |....|..|.|.|:.||...|:.|.....:...|:||..:|.| :.|.|  ..|....|.|:...
Frog   526 KRSMSLKVHSLQHSGEKPFKCENCHERFQYKYQLRSHMSIHIGHKQFMC--QWCGKDFNMKQYFD 588

  Fly   344 LHIETH---KQGRDFICEVCGCKFSQSKNLKRHALKHTENGPNRYKCQLCGFSSHRSDKMKEHVQ 405
            .|::||   ::.:.||||:||..|:...|:|||...||  |...|.|.:||.....|:.:|.|.:
Frog   589 EHMKTHTGKEREKPFICEICGKSFTSRPNMKRHRRTHT--GEKPYPCNVCGQRFRFSNMLKAHRE 651

  Fly   406 R 406
            :
Frog   652 K 652

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Plzf	NP_001285862.1	COG5048	<193..403	CDD:227381	68/218 (31%)
		C2H2 Zn finger	214..234	CDD:275368	4/19 (21%)
		C2H2 Zn finger	244..264	CDD:275368	6/19 (32%)
		C2H2 Zn finger	272..292	CDD:275368	9/19 (47%)
		C2H2 Zn finger	300..320	CDD:275368	5/19 (26%)
		C2H2 Zn finger	330..349	CDD:275368	4/18 (22%)
		C2H2 Zn finger	357..377	CDD:275368	9/19 (47%)
		C2H2 Zn finger	387..408	CDD:275368	6/20 (30%)
zbtb47	XP_004915642.1	BTB_POZ_ZBTB47_ZNF651	29..143	CDD:349540
		2A1904	<216..356	CDD:273344
		CobT2	<309..>359	CDD:226920
		PLN03086	<399..493	CDD:178635	25/96 (26%)
		C2H2 Zn finger	406..427	CDD:275370	7/22 (32%)
		C2H2 Zn finger	433..452	CDD:275368	6/19 (32%)
		C2H2 Zn finger	460..480	CDD:275368	4/19 (21%)
		C2H2 Zn finger	490..510	CDD:275368	6/19 (32%)
		C2H2 Zn finger	518..538	CDD:275368	9/19 (47%)
		SFP1	<540..626	CDD:227516	28/87 (32%)
		C2H2 Zn finger	546..566	CDD:275368	5/19 (26%)
		C2H2 Zn finger	574..594	CDD:275368	5/21 (24%)
		COG5048	601..>650	CDD:227381	20/50 (40%)
		C2H2 Zn finger	605..625	CDD:275368	9/19 (47%)
		C2H2 Zn finger	633..650	CDD:275368	5/16 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	163	1.000	Inparanoid score	I4089
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050