DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tom70 and CG14894

DIOPT Version :9

Sequence 1:	NP_609536.1	Gene:	Tom70 / 34618	FlyBaseID:	FBgn0032397	Length:	589	Species:	Drosophila melanogaster
Sequence 2:	NP_001262636.1	Gene:	CG14894 / 41993	FlyBaseID:	FBgn0038428	Length:	263	Species:	Drosophila melanogaster

Alignment Length:	152	Identity:	48/152 - (31%)
Similarity:	74/152 - (48%)	Gaps:	21/152 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 IEKQ-AISLDG---------------TAPDQEL---ERNQKSAELG-EKLSPLKE-ANNYKTEGN 98
            :||| .::||.               |..|.||   |..::..:|. |:|:..|| |:..|.|||
  Fly    38 VEKQNQLALDDEAEQGAAGGDSIATPTTVDSELTIEELREREKDLSPEQLTANKEKADKLKVEGN 102

  Fly    99 NCYRNGKYDEAIKFYDKAIDKCPKEHRTDMAIFYQNRAASYEMLKKWSNVKEDCTASLEFNPRYA 163
            ..::|...:.|.|.|.:|:|.||.....:.|:.|.||||:...|:......:|||.::|..|.|.
  Fly   103 ELFKNDDAEGAAKTYTEALDICPSASSKERAVLYGNRAAAKIKLEANKAAIDDCTKAIELWPEYV 167

  Fly   164 KAYYRRARAHEATKDMNECLDD 185
            :...|||:.:|.....:|.|:|
  Fly   168 RVLLRRAKLYEQEDKPDEALED 189

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tom70	NP_609536.1	TPR_11	89..160	CDD:290150	25/71 (35%)
		TPR repeat	90..118	CDD:276809	10/27 (37%)
		TPR repeat	123..158	CDD:276809	10/34 (29%)
		TPR repeat	296..324	CDD:276809
		TPR_11	333..399	CDD:290150
		TPR repeat	334..362	CDD:276809
		TPR repeat	367..397	CDD:276809
		TPR repeat	402..437	CDD:276809
		TPR_16	413..477	CDD:290168
		TPR repeat	443..471	CDD:276809
		TPR repeat	476..507	CDD:276809
		TPR_11	486..539	CDD:290150
		TPR repeat	512..539	CDD:276809
CG14894	NP_001262636.1	TPR_11	93..164	CDD:290150	24/70 (34%)
		TPR repeat	94..122	CDD:276809	10/27 (37%)
		TPR_11	132..198	CDD:290150	20/58 (34%)
		TPR repeat	132..162	CDD:276809	10/29 (34%)
		TPR_1	133..166	CDD:278916	12/32 (38%)
		TPR	167..198	CDD:197478	7/23 (30%)
		TPR repeat	167..195	CDD:276809	7/23 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462425
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D594913at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.850