DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tom70 and aipr-1

DIOPT Version :9

Sequence 1:	NP_609536.1	Gene:	Tom70 / 34618	FlyBaseID:	FBgn0032397	Length:	589	Species:	Drosophila melanogaster
Sequence 2:	NP_495339.1	Gene:	aipr-1 / 174092	WormBaseID:	WBGene00016966	Length:	342	Species:	Caenorhabditis elegans

Alignment Length:	221	Identity:	50/221 - (22%)
Similarity:	80/221 - (36%)	Gaps:	50/221 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 KELDGEKKRPKAKIEKQAISLDGTAPDQ------ELERNQKSAELGEKLSPLKEANNYKTEGNNC 100
            :|||...|.|: .:......|....|||      :|:.:.|          ||.....:.:||..
Worm   148 EELDELMKNPR-PLRFVFHLLQVFEPDQYVHDSWQLDEDDK----------LKSVEALRQKGNEL 201

  Fly   101 YRNGKYDEAIKFYDKAIDKC--------PKE------HRTDMAIFYQNRAASYEMLKKWSNVKED 151
            :....|.|||..|..|:.:.        |.|      .|.::.: |.|.:..|..:......:|.
Worm   202 FVQKDYKEAIDAYRDALTRLDTLILREKPGEPEWVELDRKNIPL-YANMSQCYLNIGDLHEAEET 265

  Fly   152 CTASLEFNPRYAKAYYRRARAHEATKDMNECLDDVTATCILEMFQNNQ--TIMFADRVLKETGRL 214
            .:..|:......||.:|||:|..|...::|..:|      |::...|.  ......|.:|.....
Worm   266 SSEVLKREETNEKALFRRAKARIAAWKLDEAEED------LKLLLRNHPAAASVVAREMKIVTER 324

  Fly   215 DAEKGMRNRVPVVPSACFVNTYTRSF 240
            .|||...:||          ||::.|
Worm   325 RAEKKADSRV----------TYSKMF 340

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tom70	NP_609536.1	TPR_11	89..160	CDD:290150	16/84 (19%)
		TPR repeat	90..118	CDD:276809	8/27 (30%)
		TPR repeat	123..158	CDD:276809	7/40 (18%)
		TPR repeat	296..324	CDD:276809
		TPR_11	333..399	CDD:290150
		TPR repeat	334..362	CDD:276809
		TPR repeat	367..397	CDD:276809
		TPR repeat	402..437	CDD:276809
		TPR_16	413..477	CDD:290168
		TPR repeat	443..471	CDD:276809
		TPR repeat	476..507	CDD:276809
		TPR_11	486..539	CDD:290150
		TPR repeat	512..539	CDD:276809
aipr-1	NP_495339.1	TPR repeat	191..237	CDD:276809	10/45 (22%)
		TPR_1	191..>218	CDD:278916	7/26 (27%)
		TPR_11	192..271	CDD:290150	15/79 (19%)
		TPR repeat	242..272	CDD:276809	5/30 (17%)
		TPR_11	245..308	CDD:290150	16/69 (23%)
		TPR repeat	277..305	CDD:276809	10/33 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1535
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030