DRSC/TRiP Functional Genomics Resources

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Protein Alignment Tom70 and Y37E3.1

DIOPT Version :9

Sequence 1:NP_609536.1 Gene:Tom70 / 34618 FlyBaseID:FBgn0032397 Length:589 Species:Drosophila melanogaster
Sequence 2:NP_490922.1 Gene:Y37E3.1 / 171762 WormBaseID:WBGene00021346 Length:402 Species:Caenorhabditis elegans


Alignment Length:304 Identity:70/304 - (23%)
Similarity:133/304 - (43%) Gaps:44/304 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly   267 LAFLEEKYEEIIPACTEEIESSEAEAQYKVEALLMRGTFHLLCGSYVESQQDFDAIIANDYA-DP 330
            |...:..|.:..|..:::.|::         |::.:|      |.::  |:....||:...| |.
 Worm     8 LEIFKRMYFKNYPTSSKDEEAA---------AVIQKG------GEFI--QEILPTIISTSRAYDT 55

  Fly   331 NLRAYAYIKRAALYIQL-DQREKGIADFAEAERLNPENPDVYHQRAQILLLLEQIEPALAEFEKA 394
            |.:|....:...:|..| |..|......:::.|:||:|.|.:|:....::....:|.|.:.|:.|
 Worm    56 NQKALLLAEGGKMYNVLEDYNETAEKMLSKSVRMNPKNADAWHELGLCVMKRRDLEFAQSCFKIA 120

  Fly   395 VSIAPNH-------------AIAFVQKCYAEYRLSL--LAGDQRRLESVMHTFQNAIERFPSCVE 444
            :.|:...             |:...:...||.|...  |..:.|||:|.......|..  .....
 Worm   121 LGISKTAPILTSLAVAMRLVALEHPEPAQAEIRTKAMELIIEARRLDSAYGPANIAFA--TGLFY 183

  Fly   445 CYSLTAQVLADQQQFTQAEEYYKKAM--VLAPTNPALIVHQAIMVLQWRGDINLAVQLLNKAIEV 507
            |:..||:|  :.:...:..|.||||:  .|:.|:|.:.::.| ..|::....:.|:.:|.||:|.
 Worm   184 CFFSTAKV--ELKFLDKVIENYKKALECELSRTDPQVYINMA-TCLKFMEKYDEALAVLQKAVEY 245

  Fly   508 DPKCEL-AYETLGTVEVQRAQLTRAVELFEKALLYAKSQAELVH 550
            ||:.|| ..|.|.:.....::.|.|::  :|..:.||...|:::
 Worm   246 DPRNELETREKLASFVSYLSKFTDAIQ--KKGKMKAKRMQEMIN 287

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Tom70NP_609536.1 TPR_11 89..160 CDD:290150
TPR repeat 90..118 CDD:276809
TPR repeat 123..158 CDD:276809
TPR repeat 296..324 CDD:276809 5/27 (19%)
TPR_11 333..399 CDD:290150 16/66 (24%)
TPR repeat 334..362 CDD:276809 5/28 (18%)
TPR repeat 367..397 CDD:276809 7/29 (24%)
TPR repeat 402..437 CDD:276809 10/36 (28%)
TPR_16 413..477 CDD:290168 18/67 (27%)
TPR repeat 443..471 CDD:276809 9/29 (31%)
TPR repeat 476..507 CDD:276809 7/30 (23%)
TPR_11 486..539 CDD:290150 15/53 (28%)
TPR repeat 512..539 CDD:276809 7/27 (26%)
Y37E3.1NP_490922.1 TPR_11 60..125 CDD:290150 15/64 (23%)
TPR repeat 93..123 CDD:276809 7/29 (24%)
TPR_11 <196..247 CDD:290150 15/51 (29%)
TPR repeat 215..245 CDD:276809 7/30 (23%)
TPR_1 216..249 CDD:278916 10/33 (30%)
TTC5_OB 276..394 CDD:293274 3/12 (25%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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