DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tom70 and aip

DIOPT Version :9

Sequence 1:	NP_609536.1	Gene:	Tom70 / 34618	FlyBaseID:	FBgn0032397	Length:	589	Species:	Drosophila melanogaster
Sequence 2:	NP_001096219.1	Gene:	aip / 100124770	XenbaseID:	XB-GENE-947114	Length:	328	Species:	Xenopus tropicalis

Alignment Length:	199	Identity:	44/199 - (22%)
Similarity:	76/199 - (38%)	Gaps:	53/199 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 PD-QELERNQKSAELGEKLSPLKEANNYK-------------------TEGNNCYRNGKYDEAIK 111
            || .||::|.:.......|..::|..:|:                   .|||..|:.||.::|..
Frog   135 PDLDELQKNPQLLIFIITLLQVQEPGSYRQDAWAMTDQEKMEAVPVLHQEGNQLYKQGKTNDAAA 199

  Fly   112 FYDKAIDKCPKEHR-----------------TDMAIFYQNRAASYEMLK-KWSNVKEDCTASLEF 158
            .|.:|| .|.|..:                 |.:.:.|    ...::|: .:..|.|.|::.|..
Frog   200 KYYEAI-ACLKSLQMKEQPGSPDWIALDLKITPLLLNY----CQCKLLEGDYYQVLEHCSSILNK 259

  Fly   159 NPRYAKAYYRRARAHEATKDMNECLDDVTATCILEMFQNNQTIMFADRVLKETGRLDA---EKGM 220
            .....||.::|.|||.|..:.:|...|.:....|:.       ..|..|.||..:|:.   ||.:
Frog   260 YSDNVKALFKRGRAHAAVWNASEAERDFSRAVSLDP-------SLAPLVAKEMKKLEERLHEKNL 317

  Fly   221 RNRV 224
            .:::
Frog   318 EDKI 321

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tom70	NP_609536.1	TPR_11	89..160	CDD:290150	21/107 (20%)
		TPR repeat	90..118	CDD:276809	10/46 (22%)
		TPR repeat	123..158	CDD:276809	7/52 (13%)
		TPR repeat	296..324	CDD:276809
		TPR_11	333..399	CDD:290150
		TPR repeat	334..362	CDD:276809
		TPR repeat	367..397	CDD:276809
		TPR repeat	402..437	CDD:276809
		TPR_16	413..477	CDD:290168
		TPR repeat	443..471	CDD:276809
		TPR repeat	476..507	CDD:276809
		TPR_11	486..539	CDD:290150
		TPR repeat	512..539	CDD:276809
aip	NP_001096219.1	FKBP_C	28..>89	CDD:388582
		3a0801s09	169..>320	CDD:273380	36/162 (22%)
		TPR repeat	180..206	CDD:276809	10/26 (38%)
		TPR repeat	229..259	CDD:276809	7/33 (21%)
		TPR repeat	264..292	CDD:276809	9/27 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1535
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030