DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Wdr81 and AT1G58230

DIOPT Version :9

Sequence 1:	NP_609535.1	Gene:	Wdr81 / 34616	FlyBaseID:	FBgn0032395	Length:	1953	Species:	Drosophila melanogaster
Sequence 2:	NP_001322631.1	Gene:	AT1G58230 / 842191	AraportID:	AT1G58230	Length:	2604	Species:	Arabidopsis thaliana

Alignment Length:	846	Identity:	188/846 - (22%)
Similarity:	292/846 - (34%)	Gaps:	260/846 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 WPE---IGVDPQHVCEAGGDGRFQVICDKAW---LQSLERNR---RLTHFPSWPLLDRRSYPIGQ 63
            |.|   :.|...|      :.:.|.:.:| |   |:||...|   ..|.||: .:|:|  :.:.:
plant  1589 WDENRRVSVQLSH------EEQQQNVTEK-WIHMLRSLMDERGPWSATPFPN-NILNR--WKLDR 1643

  Fly    64 LEHPWTRILVQTYRKQPQ-SRVYPL------PRISGDAPSSELPLSYSQAVSFVAHSNFKQLWEE 121
            .|..|        |::|: .|.|..      |..:..|..:|.....:::.|.|.|.      .|
plant  1644 TEDSW--------RRRPKLRRNYHFDERLCHPPSTSTATENETSNVINESKSGVIHI------PE 1694

  Fly   122 AYRKYNGAHVRMCRSTPSAPSTKPPSGQGQLQ----PHDVVLKELIQRVYRCPVLHCQLDRDGVS 182
            ..:|:....:|.......:.|.:..|.|.:..    ..|:...||::.....        :|.|.
plant  1695 QMKKFLLKGIRRITDEGGSDSCENDSSQAEQSFMDTSADIQFSELVRTSSGL--------KDVVQ 1751

  Fly   183 DSSNATSCSAGSCHANVLPALVAIETSTHISVFFYPPALECSLYDCITFSP--ALLGKNYNKTLF 245
            |..:|:|...|:  :.||.::                       .|:..:|  .|.|     .|.
plant  1752 DKVDASSLEVGT--SEVLTSV-----------------------PCVLVTPKRKLAG-----WLA 1786

  Fly   246 VIYQILQLAKHLQGQGLFLG-----------DLRLQDIVLREN-----LWLQVLPRLQCNLLDDD 294
            |:..:|    |..|:.|..|           ..:..|:...||     .|..  |......||.:
plant  1787 VMKNVL----HFSGEFLVEGTGGSAVFKNFSTSKGSDVTKAENKQNLVKWSS--PYDSETFLDLE 1845

  Fly   295 PAGEDMSPL------------------------------------TPLVSEDLGEAREAQQA--- 320
            ...::..||                                    .|.|..:....:.|::.
plant  1846 SGNKNKKPLKKVKRHRRWKIGKVKSVHWTRYLLQYTALEIFFQESVPPVFLNFASQKNAKEVGML 1910

  Fly   321 -------------LPSSST----MFDLRFAYDPAHFNLREYTEMWCNGQLSNFDYLTILNNACGR 368
                         :|...|    ..|.|.|.:.|    ....:.|...:::||:||.|||...||
plant  1911 IVSTRNEFLFPKNVPRDRTAMISFVDRRIAMEMA----ETARDRWRRREITNFEYLMILNTLAGR 1971

  Fly   369 SLTNAAYHHIMPWVT--------DFSGRGGGAWRDLTK-------SKYRLNKGDVHL----DLMY 414
            |..:...:.:.|||.        |||  ....:|||:|       .::.:.:...|.    |:..
plant  1972 SYNDLTQYPVFPWVVADYSSETLDFS--KASTFRDLSKPVGALDTRRFEIFEDRYHSFSDPDIPS 2034

  Fly   415 AHASQHGSADGSYQAIGDQAPHHVSDFLSEITYFVYMARRTPQSILCAHVRPIWVPAEYPVSIQR 479
            .:...|.|:.||           |..:|..:..|..: .|:.|.....|...::...|  .|.:.
plant  2035 FYYGSHYSSMGS-----------VLYYLLRLEPFTSL-HRSLQGGKFDHADRLFQSVE--GSFRN 2085

  Fly   480 LQEWTPD--ECIPEFYSDPMIF---KSIH-------EDLPDLELPAWAT-CPEDFICKHREALES 531
            ....|.|  |.||||:..|...   .|.|       |.|.::.||.||. .||.||.::||||||
plant  2086 CLSNTSDVKELIPEFFYMPEFLVNSNSYHLGVKQDGEPLGEVCLPPWAKGSPEMFIARNREALES 2150

  Fly   532 QYVSERLHHWIDLNFGYKLSGKAAVKSKNVCLTLV--------------------DQHRNLSQRG 576
            :|||..||.||||.||:|..||.||::.|:...|.                    ||..|..|..
plant  2151 EYVSSHLHDWIDLIFGHKQRGKPAVEAANIFYYLTYEGAVDVENMEDQLQISAIEDQIANFGQTP 2215

  Fly   577 IVQLFASAHPPRRYATPWFSRTAPRLSQLYASPA-----KRLAKSTENLQAESATGSSHLSLRLG 636
            | |:|...||.|       ....|....||.:||     ..|..:|.:..|....|....::.|.
plant  2216 I-QIFRKKHPRR-------GPPIPIAHPLYFAPASINLSSILPATTHSPSAVLYVGVVDSNIVLV 2272

  Fly   637 DDGSSGSV--------HSS---SASASASNFYAITNFIELPENYNPALLLHNLET-LEAFYARTF 689
            :.|.:.||        ||.   :.|::...|:.:.:.:..|.|.. :.|..|:|. .:.|.|...
plant  2273 NQGLTLSVKIWLTTQLHSGGNFTFSSAQDPFFGVGSDVLSPRNIG-SPLADNVELGSQCFAAMQM 2336

  Fly   690 P 690
            |
plant  2337 P 2337

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Wdr81	NP_609535.1	Beach	345..588	CDD:100117	88/294 (30%)
		WD40	<1644..1877	CDD:225201
		WD40	1651..1876	CDD:295369
		WD40 repeat	1662..1705	CDD:293791
		WD40 repeat	1710..1744	CDD:293791
		WD40 repeat	1752..1788	CDD:293791
		WD40 repeat	1799..1836	CDD:293791
AT1G58230	NP_001322631.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D101142at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920