Protein Alignment Wdr81 and Wdfy4

DIOPT Version :10

• Sequence 1: NP_609535.1
• Gene: Wdr81 / 34616
• FlyBaseID: FBgn0032395
• Length: 1953
• Species: Drosophila melanogaster
• Sequence 2: NP_001414587.1
• Gene: Wdfy4 / 498582
• RGDID: 1564142
• Length: 3187
• Species: Rattus norvegicus
• Alignment Length: 858
• Identity: 185/858 - (21%)
• Similarity: 280/858 - (32%)
• Gaps: 322/858 - (37%)

  Fly    53 LLDRRSYPIG-QLE-----HPWTRILVQTYRKQPQSRVYPLPRISGDAPSS-------------- 97
            ||:.||||.| .||     :|:.::.:....:....:...||.: ||...|
  Rat  2062 LLNARSYPEGFGLEPKPRINPYHQVFLSPSEEVKDKKEEGLPSL-GDVQHSIQKSVRALWQQLVA 2125

  Fly    98 ----------ELPLSYSQAVSFVAHSNFKQLWEE----AYRKYNGAHVRMCRSTPSAP-STKPPS 147
                      ::.||.....|.|.......||||    |::.|..:..:...|..|.. .:|..|
  Rat  2126 QRRQTLEDAFKIDLSVKAGESEVKIEEVTPLWEETMLRAWQHYLASEKKSLASRSSVTHHSKATS 2190

  Fly   148 GQGQL-----------------QPHDVVL---------KELIQRVYRCPVLHCQLDRDGVSDSS- 185
            ..|.|                 :..|.|.         :||...:|:..|.  :..||.:..::
  Rat  2191 WSGSLSSAMRLMPGRQAKDPECRAEDFVSCIENYRRKGQELYASIYKDYVQ--RRKRDSIKAATA 2253

  Fly   186 -------------------NATSCS---------------------------AGSCHAN------ 198
                               .:||||                           .|||..:
  Rat  2254 WARMQEQLFGELGLWGRMRESTSCSQWELDRREGPARMRKRIRRLCAWETLNLGSCKESQDQRGD 2318

  Fly   199 ---------VLPAL-----VAIETS-----------THISVFFYPPALECSLYD------C---- 228
                     |.|..     :.||.:           |.::.|   |||..||:.      |
  Rat  2319 VSQTNAENQVCPVFRIADELTIEEAESRPDEVGVDCTQLTFF---PALHESLHSEDFLELCRERQ 2380

  Fly   229 ITFSPALLGKNYN-KTLFVIYQILQLAKHLQGQGLFLGDLRLQDIVLRENLWLQVLPRLQC---- 288
            |.....|.|:..: |...||.|     .||..:|:.|  ...|...:.||..|.....:.|
  Rat  2381 IILQELLDGEKVSQKVPMVIVQ-----GHLVSEGILL--FGQQHFYVCENFTLSPTGDVYCTHHC 2438

  Fly   289 ----------NLLDDDPAGEDMSPLTPLVSEDLGEAREAQQALPSSSTMFDLRFAY--------- 334
                      |:...|.:.:..|......| ||.|.|:|:..|...:.....:..|
  Rat  2439 LSNISDPFIFNMCSKDRSSDHYSCQRHAYS-DLRELRQARFLLQDIALEIFFQNGYSKLLVFYNS 2502

  Fly   335 -----------------------DPAHFNLREY-------TEMWCNGQLSNFDYLTILNNACGRS 369
                                   ||  ||||.:       .:.|...::|||:||..||...||:
  Rat  2503 DRSKAFKSFCTFQPSLKGKGTTEDP--FNLRRHPGFDRTMLQKWQKREMSNFEYLMYLNTLAGRT 2565

  Fly   370 LTNAAYHHIMPWV-TDFSGR-----GGGAWRDLTK-----SKYRLNK------------GDVHLD 411
            ..:...:.:.||| .|::..     ....:|||:|     ||.|..|            ||:.:.
  Rat  2566 YNDYMQYPVFPWVLADYTSEMLNLTNPKTFRDLSKPMGAQSKERKLKFTQRFKDIEKIEGDMTVQ 2630

  Fly   412 LMYAHASQHGSADGSYQAIGDQAPHHVSDFLSEITYFVYMARRTP-QSILCA------------- 462
            .                       |:.:.:.|.|....|:.|..| ....|:
  Rat  2631 C-----------------------HYYTHYSSAIIVASYLVRMPPFTQAFCSLQGGSFDVADRMF 2672

  Fly   463 -HVRPIWVPAEYPVSIQRLQEWTPD-ECIPEFYS--DPMIFKSIHE--DLPDLELPAWAT-CPED 520
             .|:..|..|. ..::..::|.||: ..:|||.:  :.:.|..:.:  .|.|::||.||. .|..
  Rat  2673 HSVKNTWESAS-KENMSDVRELTPEFFYLPEFLTNCNAVEFGRMQDGTTLGDVQLPPWADGDPRK 2736

  Fly   521 FICKHREALESQYVSERLHHWIDLNFGYKLSGKAAVKSKNV-----------CLTLVDQHRNLSQ 574
            ||..||:||||.:||..|||||||.||||..|.|||::.|.           ..::.|.....:.
  Rat  2737 FISLHRQALESDFVSSNLHHWIDLIFGYKQQGPAAVEAVNTFHPYFYGDRIDLSSITDPLIKSTI 2801

  Fly   575 RGIV--------QLFASAHPPR----RYATPWFSRTAP------RLSQLYASPAKRLAKSTE--- 618
            .|.|        |:|...||.|    :...|....:.|      ..|.|::.||.|.::.|.
  Rat  2802 LGFVSNFGQVPKQIFTKPHPSRNTTGKSPVPGKETSTPTGLPGHSQSFLHSLPALRPSQVTVKDM 2866

  Fly   619 ---NLQAESATGS 628
               :|.:||..|:
  Rat  2867 YLFSLGSESPKGA 2879

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wdr81	NP_609535.1	Beach	345..588	CDD:100117	81/305 (27%)
		WD40	1651..1876	CDD:475233
		WD40 repeat	1662..1705	CDD:293791
		WD40 repeat	1710..1744	CDD:293791
		WD40 repeat	1752..1788	CDD:293791
		WD40 repeat	1799..1836	CDD:293791
Wdfy4	NP_001414587.1	None