DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Wdr81 and CG10931

DIOPT Version :9

Sequence 1:	NP_609535.1	Gene:	Wdr81 / 34616	FlyBaseID:	FBgn0032395	Length:	1953	Species:	Drosophila melanogaster
Sequence 2:	NP_611261.1	Gene:	CG10931 / 37024	FlyBaseID:	FBgn0034274	Length:	345	Species:	Drosophila melanogaster

Alignment Length:	262	Identity:	50/262 - (19%)
Similarity:	111/262 - (42%)	Gaps:	41/262 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly  1610 AYKLDQMPKTRHLKGNWLAYWRNETTRNEKDTQTLNLKQIRLQSFVGHTNSVRAIYALDNENSFI 1674
            ::|:..:|...||:.:....:..:                  .|.:||:..|..:....|..:.:
  Fly    26 SFKMPMLPSQFHLENSMSPGYAIK------------------HSLLGHSGCVTGLKFSSNGENLV 72

  Fly  1675 SASKDKTVKLWSLRSEGDGRKTSACQFTYTAHKKSINSLGFLESLRYVVSC--DSGIHLWDPFIG 1737
            |:|.|:.:|||.|       ..:.|..:...|...:|.:.: .:...:.||  |..:.|||....
  Fly    73 SSSGDRLLKLWDL-------SATRCIQSLAGHGDGVNDVAW-SAAGLIASCSDDMTVRLWDARSK 129

  Fly  1738 RPLSVLDAPRHSAVTVVKCLPSHSPLVIAGTAESTVKMVDARSCEYVNEWRVCNASLPNATVRCL 1802
            ..:.||:.  ||..:...|....:.|:.:.:.:.||::.|.|:.:.:   ::.:|.  ...:..:
  Fly   130 LCVKVLEG--HSRYSFSCCFNPQANLLASTSFDETVRLWDVRTGKTL---KIVHAH--QDPITSV 187

  Fly  1803 AVAPSGNWLAAGLSSGCIVQLDTRTGMVINSWRPMECDLLQLA----APSDQFLVSSALDHSLAV 1863
            .....||........|.:...|:.||.|:.:.  ::.|.:.:.    :|:.::::||.|:::|.:
  Fly   188 DFHRDGNIFVTSSYDGLVRLWDSSTGHVLKTL--VDVDNIPVGYVKFSPNGRYILSSTLNNTLRL 250

  Fly  1864 WH 1865
            |:
  Fly   251 WN 252

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Wdr81	NP_609535.1	Beach	345..588	CDD:100117
		WD40	<1644..1877	CDD:225201	46/228 (20%)
		WD40	1651..1876	CDD:295369	46/221 (21%)
		WD40 repeat	1662..1705	CDD:293791	9/42 (21%)
		WD40 repeat	1710..1744	CDD:293791	8/35 (23%)
		WD40 repeat	1752..1788	CDD:293791	6/35 (17%)
		WD40 repeat	1799..1836	CDD:293791	7/36 (19%)
CG10931	NP_611261.1	WD40	<48..341	CDD:225201	46/240 (19%)
		WD40	49..341	CDD:238121	46/239 (19%)
		WD40 repeat	59..96	CDD:293791	10/43 (23%)
		WD40 repeat	102..137	CDD:293791	9/35 (26%)
		WD40 repeat	142..178	CDD:293791	6/38 (16%)
		WD40 repeat	185..220	CDD:293791	7/36 (19%)
		WD40 repeat	227..263	CDD:293791	6/26 (23%)
		WD40 repeat	271..309	CDD:293791
		WD40 repeat	314..340	CDD:293791
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442355
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930