Protein Alignment Wdr81 and lyst-1

DIOPT Version :9

• Sequence 1: NP_609535.1
• Gene: Wdr81 / 34616
• FlyBaseID: FBgn0032395
• Length: 1953
• Species: Drosophila melanogaster
• Sequence 2: NP_510030.2
• Gene: lyst-1 / 181379
• WormBaseID: WBGene00011361
• Length: 2760
• Species: Caenorhabditis elegans
• Alignment Length: 539
• Identity: 115/539 - (21%)
• Similarity: 198/539 - (36%)
• Gaps: 151/539 - (28%)

  Fly   341 LREYTEMWCNGQLSNFDYLTILNNACGRSLTNAAYHHIMPWVTDFSGRGGGAWRDL-TKSKYRLN 404
            |..||:.|..|::|||:|||:||...||::.:::...|.|.:.   .:.|....|| .|:.||
 Worm  2083 LLAYTKRWEEGKMSNFEYLTMLNLFAGRTIHDSSSSPIFPRIL---AKFGDKSVDLQDKTIYR-- 2142

  Fly   405 KGDVHLDLMYA---------HASQHGSADGSYQAIGDQAPHHVSDFLSEITYFVYMARRTPQSIL 460
                .||...|         | .:|.:.....:.|....|:|.....|         .|...|..
 Worm  2143 ----KLDRPVAAQDPVSVEKH-KEHYNELKENEEISHLTPYHFGSMCS---------NRGVVSFF 2193

  Fly   461 CAHVRPIWVPAEYPVSIQRLQEWTPD----------------------ECIPEFYSDPMIFKSIH 503
            ...:.|.   .|..:.:|..:...||                      |.:||.::...:.::.:
 Worm  2194 NIRLLPF---GEEAIELQDGRFDFPDRLFHNIESGLGLGKIESSNDYKELVPELFTTVEVLRNDN 2255

  Fly   504 ----------EDLPDLELPAWA-----TCPEDFICKHREALESQYVSERLHHWIDLNFGYKLSGK 553
                      |.:.|:::|.|.     ...|:||..||.||||:.|...|||||||.||||..||
 Worm  2256 GNQFGEKQNGETVNDVDVPQWCYMDEKAVHENFIYLHRHALESEIVQSMLHHWIDLVFGYKSRGK 2320

  Fly   554 AAVKSKNVCLTLV------------------DQHRNLSQRGIVQLFASAHPPRRYATPWFSRTAP 600
            :|..:.||....|                  :.::.......:|||..:||.|....  ..|::.
 Worm  2321 SAHDAINVYHPAVYPGNSPPPSFDRVMTNAYEANQKTLGTAPIQLFTQSHPKREVLQ--HRRSSV 2383

  Fly   601 R------------LSQ-------LYASPAKRLAKSTENLQAE---SATGS--------------- 628
            |            :.|       :.....:|:.:..:||:::   .|..|
 Worm  2384 RNMHGLAFGKELTIGQYDVGEYTMDTQTTQRVWRRMKNLKSKIFNKANASDQENFHLFQKNRDKR 2448

  Fly   629 ----SHLSLRLGDDG---SSGSVHSSSASASASNFYAITNFIELPENYNPALLLHN-LETLEAFY 685
                |.:|.::.:|.   |.|  :|..:...|....|::    :.:||...:||.. :|..:..|
 Worm  2449 EKDPSDISFKIKEDQLILSDG--NSEISKGHAQKIEAVS----VDDNYVACMLLRGPIEIYKMAY 2507

  Fly   686 ARTFPQQRASANPEEKMISSDLMFEQNSA----EHSFTNQLFASGDELPPKSKNLLREKRNCLQH 746
             |.:.:.|.:.:...:..:.:|:.|....    |..:|:.      |:......:....:|..:.
 Worm  2508 -RQYSKSRIAVDRVLRSDNKELVIEYCGTLPVQEGHYTDV------EVCTSFSTIFTIHKNENKS 2565

  Fly   747 LLNVRKERDLHVLGCLIIE 765
            :::|......|:.||..||
 Worm  2566 IISVWNLHTHHIRGCCTIE 2584

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wdr81	NP_609535.1	Beach	345..588	CDD:100117	76/307 (25%)
		WD40	<1644..1877	CDD:225201
		WD40	1651..1876	CDD:295369
		WD40 repeat	1662..1705	CDD:293791
		WD40 repeat	1710..1744	CDD:293791
		WD40 repeat	1752..1788	CDD:293791
		WD40 repeat	1799..1836	CDD:293791
lyst-1	NP_510030.2	Beach	2087..2373	CDD:214982	76/307 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1786
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D101142at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910