DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Rh5 and ninaE

DIOPT Version :9

Sequence 1:	NP_001285859.1	Gene:	Rh5 / 34615	FlyBaseID:	FBgn0014019	Length:	382	Species:	Drosophila melanogaster
Sequence 2:	NP_524407.1	Gene:	ninaE / 42367	FlyBaseID:	FBgn0002940	Length:	373	Species:	Drosophila melanogaster

Alignment Length:	364	Identity:	135/364 - (37%)
Similarity:	198/364 - (54%)	Gaps:	22/364 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 LGDGSVFPMGHGYPAEYQHMVHAHWRGFREA-PIYYHAGFYIAFIVLM-LSSIFGNGLVIWIFST 79
            |.:|||...   ...:..|::..:|..|... ||:  |....|::::: :.|..|||:||:||:|
  Fly    18 LSNGSVVDK---VTPDMAHLISPYWNQFPAMDPIW--AKILTAYMIMIGMISWCGNGVVIYIFAT 77

  Fly    80 SKSLRTPSNLLILNLAIFDL-FMCTNMPHYLINATVGYIVGGDLGCDIYALNGGISGMGASITNA 143
            :||||||:|||::||||.|. .|.||.|...||......|.|.:.|||||..|...|..:..:..
  Fly    78 TKSLRTPANLLVINLAISDFGIMITNTPMMGINLYFETWVLGPMMCDIYAGLGSAFGCSSIWSMC 142

  Fly   144 FIAFDRYKTISNPIDGR-----LSYGQIVLLILFTWLWATPFSVLPLFQIWGRYQPEGFLTTCSF 203
            .|:.|||:.|...:.||     |:.|:|.    :.|..::.:.:.|.|. |.||.|||.||:|..
  Fly   143 MISLDRYQVIVKGMAGRPMTIPLALGKIA----YIWFMSSIWCLAPAFG-WSRYVPEGNLTSCGI 202

  Fly   204 DYLTNTDENRLFVRTIFVWSYVIPMTMILVSYYKLFTHVRVHEKMLAEQAKKMNVKSLSANANAD 268
            |||......|.::....::.|.||:.:|..||:.:...|..|||.:.|||||||||||.::.:|:
  Fly   203 DYLERDWNPRSYLIFYSIFVYYIPLFLICYSYWFIIAAVSAHEKAMREQAKKMNVKSLRSSEDAE 267

  Fly   269 NMSVELRIAKAALIIYMLFILAWTPYSVVALIGCFGEQQLITPFVSMLPCLACKSVSCLDPWVYA 333
            . |.|.::||.||:...|:.:|||||.|:..:|.|..:.| ||..::......||.:|.:|.||.
  Fly   268 K-SAEGKLAKVALVTITLWFMAWTPYLVINCMGLFKFEGL-TPLNTIWGACFAKSAACYNPIVYG 330

  Fly   334 TSHPKYRLELERRLPWLGIREKHATSGTSGGQESVASVS 372
            .|||||||.|:.:.|.....:  ...|.|...:|.|:.|
  Fly   331 ISHPKYRLALKEKCPCCVFGK--VDDGKSSDAQSQATAS 367

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rh5	NP_001285859.1	7tm_4	60..>236	CDD:304433	69/182 (38%)
Rh5	NP_001285859.1	7tm_1	69..332	CDD:278431	107/268 (40%)
ninaE	NP_524407.1	7tmA_photoreceptors_insect	52..340	CDD:320207	118/294 (40%)
		TM helix 1	53..77	CDD:320207	9/23 (39%)
		TM helix 2	86..108	CDD:320207	12/21 (57%)
		TM helix 3	124..146	CDD:320207	7/21 (33%)
		TM helix 4	168..184	CDD:320207	3/19 (16%)
		TM helix 5	212..235	CDD:320207	6/22 (27%)
		TM helix 6	275..297	CDD:320207	11/21 (52%)
		TM helix 7	308..333	CDD:320207	7/24 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461673
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm42416
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24240
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.940