DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Rh5 and Rh2

DIOPT Version :9

Sequence 1:NP_001285859.1 Gene:Rh5 / 34615 FlyBaseID:FBgn0014019 Length:382 Species:Drosophila melanogaster
Sequence 2:NP_524398.1 Gene:Rh2 / 42261 FlyBaseID:FBgn0003248 Length:381 Species:Drosophila melanogaster


Alignment Length:344 Identity:131/344 - (38%)
Similarity:190/344 - (55%) Gaps:9/344 - (2%)


- Green bases have known domain annotations that are detailed below.


  Fly     7 SGPQAYVNDSLGDGSVFPMGHGYPAEYQHMVHAHWRGFREAPIYYHAGFYIAFIVLMLSSIFGNG 71
            |||: :...|.|:|||  :.:..| :..|:|:.:|..|............:..:.:|:.|..|||
  Fly    16 SGPR-FQAQSSGNGSV--LDNVLP-DMAHLVNPYWSRFAPMDPMMSKILGLFTLAIMIISCCGNG 76

  Fly    72 LVIWIFSTSKSLRTPSNLLILNLAIFDL-FMCTNMPHYLINATVGYIVGGDLGCDIYALNGGISG 135
            :|::||..:||||||:|||:||||..|. .|.:..|..:||......|.|.|.|||||..|.:.|
  Fly    77 VVVYIFGGTKSLRTPANLLVLNLAFSDFCMMASQSPVMIINFYYETWVLGPLWCDIYAGCGSLFG 141

  Fly   136 MGASITNAFIAFDRYKTISNPIDGR-LSYGQIVLLILFTWLWATPFSVLPLFQIWGRYQPEGFLT 199
            ..:..:...||||||..|...|:|. ::....::.|||.|:.|..::|:||.. |..|.|||.||
  Fly   142 CVSIWSMCMIAFDRYNVIVKGINGTPMTIKTSIMKILFIWMMAVFWTVMPLIG-WSAYVPEGNLT 205

  Fly   200 TCSFDYLTNTDENRLFVRTIFVWSYVIPMTMILVSYYKLFTHVRVHEKMLAEQAKKMNVKSLSAN 264
            .||.||:|.....|.::.|..::.|..|:.:|..||:.:...|..|||.:.|||||||||||.::
  Fly   206 ACSIDYMTRMWNPRSYLITYSLFVYYTPLFLICYSYWFIIAAVAAHEKAMREQAKKMNVKSLRSS 270

  Fly   265 ANADNMSVELRIAKAALIIYMLFILAWTPYSVVALIGCFGEQQLITPFVSMLPCLACKSVSCLDP 329
            .:.|. |.|.::||.||....|:.:|||||.|:...|.|....| ||..::......|:.:..:|
  Fly   271 EDCDK-SAEGKLAKVALTTISLWFMAWTPYLVICYFGLFKIDGL-TPLTTIWGATFAKTSAVYNP 333

  Fly   330 WVYATSHPKYRLELERRLP 348
            .||..||||||:.|:.:.|
  Fly   334 IVYGISHPKYRIVLKEKCP 352

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Rh5NP_001285859.1 7tm_4 60..>236 CDD:304433 71/177 (40%)
7tm_1 69..332 CDD:278431 106/264 (40%)
Rh2NP_524398.1 7tm_4 67..>237 CDD:304433 69/170 (41%)
7tm_1 74..336 CDD:278431 106/264 (40%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45461674
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 1 1.000 - - otm42416
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
32.840

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