DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rh5 and opn4.1

DIOPT Version :9

Sequence 1:	NP_001285859.1	Gene:	Rh5 / 34615	FlyBaseID:	FBgn0014019	Length:	382	Species:	Drosophila melanogaster
Sequence 2:	NP_840074.2	Gene:	opn4.1 / 352918	ZFINID:	ZDB-GENE-030314-2	Length:	500	Species:	Danio rerio

Alignment Length:	374	Identity:	118/374 - (31%)
Similarity:	198/374 - (52%)	Gaps:	34/374 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 HGYPAEYQHMVHAHWRGFREAPIYYHAGFYIAFIVLM--LSSIFGNGLVIWIFSTSKSLRTPSNL 89
            || |....|  |.....|....:..||.:.|..::|:  ::.:.||.||:::|..|::|||..|:
Zfish    40 HG-PTHSHH--HDPPHPFPTVDVPDHAHYIIGSVILIVGITGVIGNALVVYVFCRSRTLRTAGNM 101

  Fly    90 LILNLAIFDLFM-CTNMPHYLINATVGYIVGGDLGCDIYALNGGISGMGASITNAFIAFDRYKTI 153
            .|:|||:.|..| .|..|.:...:.....|.|:..|::||..|.:.|:.:.:|...||.||...|
Zfish   102 FIVNLAVADFLMSVTQSPVFFAASLHRRWVFGERPCELYAFCGALFGICSMMTLTAIAADRCLAI 166

  Fly   154 SNPID--GRLSYGQIVLLILFTWLWATPFSVLPLFQIWGRYQPEGFLTTCSFDYLTNTDENRLFV 216
            :.|:.  .|:|..:...:::..||::..:|:.|.|. |..|.|||..|:||:||:|.|...|.:.
Zfish   167 TQPLALVSRVSRRKAGAVLVVVWLYSLGWSLPPFFG-WSAYVPEGLQTSCSWDYMTFTPSVRAYT 230

  Fly   217 RTIFVWSYVIPMTMILVSYYKLFTHVRVHEKMLAE----QAKKMNVKSLSANANADNMSVELRIA 277
            ..:||:.:.||:.:|...|:.:|..:|...|.:.|    :..|:          .:.|..|.::|
Zfish   231 ILLFVFVFFIPLGIIGSCYFAIFQTIRAAGKEIRELDCGETHKV----------YERMQNEWKMA 285

  Fly   278 KAALIIYMLFILAWTPYSVVALIGCFGEQQLITPFVSMLPCLACKSVSCLDPWVYATSHPKYRLE 342
            |.||::.:|||::|:|||||||....|....:||:::.:|.:..|:.:..:|.:||.:|||||:.
Zfish   286 KVALVVIVLFIISWSPYSVVALTATAGYSHFLTPYMNSVPAVIAKASAIHNPIIYAITHPKYRVA 350

  Fly   343 LERRL----PWLGIREKHATSGTSGGQESVAS-----VSGDTLALSVQN 382
            :.|.:    |.|.::||...|..|.|  ||:|     .|..:|.:|:.|
Zfish   351 IARYIPVLRPILRVKEKDLRSSFSSG--SVSSRRPTLTSQCSLGVSMGN 397

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rh5	NP_001285859.1	7tm_4	60..>236	CDD:304433	58/180 (32%)
Rh5	NP_001285859.1	7tm_1	69..332	CDD:278431	86/269 (32%)
opn4.1	NP_840074.2	7tm_4	72..>284	CDD:304433	66/222 (30%)
		7tm_1	81..340	CDD:278431	86/269 (32%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	404..428
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170590451
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H432
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24240
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.940