DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rh5 and Opn4

DIOPT Version :9

Sequence 1:	NP_001285859.1	Gene:	Rh5 / 34615	FlyBaseID:	FBgn0014019	Length:	382	Species:	Drosophila melanogaster
Sequence 2:	NP_038915.1	Gene:	Opn4 / 30044	MGIID:	1353425	Length:	521	Species:	Mus musculus

Alignment Length:	403	Identity:	128/403 - (31%)
Similarity:	205/403 - (50%)	Gaps:	55/403 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 INGPSGPQAYVNDSLGDGSVF---PMGHGY-----------------PAEYQHMVHAHWRGFREA 47
            ::.||||:  |..||.....|   |...|.                 |....|.. |.|..|...
Mouse     1 MDSPSGPR--VLSSLTQDPSFTTSPALQGIWNGTQNVSVRAQLLSVSPTTSAHQA-AAWVPFPTV 62

  Fly    48 PIYYHAGFYIAFIVLM--LSSIFGNGLVIWIFSTSKSLRTPSNLLILNLAIFDLFM-CTNMPHYL 109
            .:..||.:.:..::|:  |:.:.||..||:.|..::.||||:|:.|:|||:.|..| .|..|.:.
Mouse    63 DVPDHAHYTLGTVILLVGLTGMLGNLTVIYTFCRNRGLRTPANMFIINLAVSDFLMSVTQAPVFF 127

  Fly   110 INATVGYIVGGDLGCDIYALNGGISGMGASITNAFIAFDRYKTISNPID--GRLSYGQIVLLILF 172
            .::.....:.|:.||:.||..|.:.|:.:.||...||.|||..|:.|:.  ||.|..:..|::|.
Mouse   128 ASSLYKKWLFGETGCEFYAFCGAVFGITSMITLTAIAMDRYLVITRPLATIGRGSKRRTALVLLG 192

  Fly   173 TWLWATPFSVLPLFQIWGRYQPEGFLTTCSFDYLTNTDENRLFVRTIFVWSYVIPMTMILVSYYK 237
            .||:|..:|:.|.|. |..|.|||.||:||:||:|.|.:.|.:...:|.:.:.:|:.:|:..|..
Mouse   193 VWLYALAWSLPPFFG-WSAYVPEGLLTSCSWDYMTFTPQVRAYTMLLFCFVFFLPLLIIIFCYIF 256

  Fly   238 LFTHVR--------VHEKMLAEQAKKMNVKSLSANANADNMSVELRIAKAALIIYMLFILAWTPY 294
            :|..:|        ..|..|.::.:...::|            |.::||.|||:.:||:|:|.||
Mouse   257 IFRAIRETGRACEGCGESPLRQRRQWQRLQS------------EWKMAKVALIVILLFVLSWAPY 309

  Fly   295 SVVALIGCFGEQQLITPFVSMLPCLACKSVSCLDPWVYATSHPKYRLELERRLPWLGIREKHATS 359
            |.|||:...|...::||::|.:|.:..|:.:..:|.:||.:|||||:.:.:.||.||:     ..
Mouse   310 STVALVAFAGYSHILTPYMSSVPAVIAKASAIHNPIIYAITHPKYRVAIAQHLPCLGV-----LL 369

  Fly   360 GTSGGQESVASVS 372
            |.| ||.|..|:|
Mouse   370 GVS-GQRSHPSLS 381

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rh5	NP_001285859.1	7tm_4	60..>236	CDD:304433	64/180 (36%)
Rh5	NP_001285859.1	7tm_1	69..332	CDD:278431	91/273 (33%)
Opn4	NP_038915.1	7tm_4	77..>244	CDD:304433	62/167 (37%)
		7tm_1	86..347	CDD:278431	91/273 (33%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	445..486
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845795
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm42416
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24240
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.940