DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rh5 and Opn4

DIOPT Version :9

Sequence 1:	NP_001285859.1	Gene:	Rh5 / 34615	FlyBaseID:	FBgn0014019	Length:	382	Species:	Drosophila melanogaster
Sequence 2:	NP_620215.1	Gene:	Opn4 / 192223	RGDID:	621701	Length:	474	Species:	Rattus norvegicus

Alignment Length:	373	Identity:	122/373 - (32%)
Similarity:	197/373 - (52%)	Gaps:	25/373 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 SVFPMGHGYPAEYQHMVHAHWRGFREAPIYYHAGFYIAFIVLM--LSSIFGNGLVIWIFSTSKSL 83
            ||.|...|..|       |.|..|....:..||.:.:..::|:  |:.:.||..||:.|..::.|
  Rat    44 SVSPTTPGLQA-------AAWVPFPTVDVPDHAHYTLGTVILLVGLTGMLGNLTVIYTFCRNRGL 101

  Fly    84 RTPSNLLILNLAIFDLFMC-TNMPHYLINATVGYIVGGDLGCDIYALNGGISGMGASITNAFIAF 147
            |||:|:||:|||:.|..|. |..|.:..::.....:.|:.||..||..|.:.|:.:.||...||.
  Rat   102 RTPANMLIINLAVSDFLMSFTQAPVFFASSLYKKWLFGETGCKFYAFCGAVFGIVSMITLTAIAM 166

  Fly   148 DRYKTISNPID--GRLSYGQIVLLILFTWLWATPFSVLPLFQIWGRYQPEGFLTTCSFDYLTNTD 210
            |||..|:.|:.  |..|..:..|::|..||:|..:|:.|.|. |..|.|||.||:||:||:|.|.
  Rat   167 DRYLVITRPLATIGMRSKRRTALVLLGVWLYALAWSLPPFFG-WSAYVPEGLLTSCSWDYVTFTP 230

  Fly   211 ENRLFVRTIFVWSYVIPMTMILVSYYKLFTHVRVHEKMLAEQAKKMNVKSLSANANADNMSVELR 275
            ..|.:...:|.:.:.:|:.:|:..|..:|..:|.     ..:|.:...:|.........:..|.:
  Rat   231 LVRAYTMLLFCFVFFLPLLIIIFCYIFIFRAIRE-----TGRACEGCGESPLRRRQWQRLQSEWK 290

  Fly   276 IAKAALIIYMLFILAWTPYSVVALIGCFGEQQLITPFVSMLPCLACKSVSCLDPWVYATSHPKYR 340
            :||.|||:.:||:|:|.|||.|||:|..|...::||::|.:|.:..|:.:..:|.:||.:|||||
  Rat   291 MAKVALIVILLFVLSWAPYSTVALVGFAGYSHILTPYMSSVPAVIAKASAIHNPIIYAITHPKYR 355

  Fly   341 LELERRLPWLGI-------REKHATSGTSGGQESVASVSGDTLALSVQ 381
            ..:.:.||.||:       |...:.|..|..:.:::|.|.|...:|.|
  Rat   356 AAIAQHLPCLGVLLGVSGQRSHPSLSYRSTHRSTLSSQSSDLSWISGQ 403

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rh5	NP_001285859.1	7tm_4	60..>236	CDD:304433	64/180 (36%)
Rh5	NP_001285859.1	7tm_1	69..332	CDD:278431	91/265 (34%)
Opn4	NP_620215.1	7tm_4	78..>245	CDD:304433	62/167 (37%)
		7tm_1	87..347	CDD:278431	91/265 (34%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	428..474
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166349212
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm44480
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24240
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.940