Protein Alignment Rh5 and Opn1mw

DIOPT Version :10

• Sequence 1: NP_477096.1
• Gene: Rh5 / 34615
• FlyBaseID: FBgn0014019
• Length: 382
• Species: Drosophila melanogaster
• Sequence 2: NP_032132.1
• Gene: Opn1mw / 14539
• MGIID: 1097692
• Length: 359
• Species: Mus musculus
• Alignment Length: 377
• Identity: 90/377 - (23%)
• Similarity: 170/377 - (45%)
• Gaps: 73/377 - (19%)

  Fly    33 YQHMVHA---------HWRGFREAPIYYHAGFYIA------FIVLMLSSIFGNGLVIWIFSTSKS 82
            |:...||         ..:|..|.|.|:.|..::.      .|:::::|:|.||||:......|.
Mouse    14 YEDSTHASIFTYTNSNSTKGPFEGPNYHIAPRWVYHLTSTWMILVVVASVFTNGLVLAATMRFKK 78

  Fly    83 LRTPSNLLILNLAIFDL---FMCTNMPHYLINATVGYIVGGDLGCDIYALNG------GISGMGA 138
            ||.|.|.:::|||:.||   .:.:.:.  ::|...||.|   ||..:..:.|      ||:|:.:
Mouse    79 LRHPLNWILVNLAVADLAETIIASTIS--VVNQIYGYFV---LGHPLCVIEGYIVSLCGITGLWS 138

  Fly   139 SITNAFIAFDRYKTISNP-----IDGRLSYGQIVLLILFTWLWATPFSVLPLFQIWGRYQPEGFL 198
            .   |.|:::|:..:..|     .|.:|:    .:.|:|:|:||..::..|:|. |.||.|.|..
Mouse   139 L---AIISWERWLVVCKPFGNVRFDAKLA----TVGIVFSWVWAAIWTAPPIFG-WSRYWPYGLK 195

  Fly   199 TTCSFDYLTNTDEN--RLFVRTIFVWSYVIPMTMILVSYYKLFTHVRVHEKMLAEQAKKMNVKSL 261
            |:|..|..:.|...  :.::..:.|...:.|:::|::.|.:::..:|.    :|:|.|:
Mouse   196 TSCGPDVFSGTSYPGVQSYMMVLMVTCCIFPLSIIVLCYLQVWLAIRA----VAKQQKE------ 250

  Fly   262 SANANADNMSVELRIAKAALIIYMLFILAWTPYSVVALIGCFGEQQ---LITPFVSMLPCLACKS 323
                :......|..:.:..:::...:.|.|.||:..|   ||....   ...|.|:.||....||
Mouse   251 ----SESTQKAEKEVTRMVVVMVFAYCLCWGPYTFFA---CFATAHPGYAFHPLVASLPSYFAKS 308

  Fly   324 VSCLDPWVYATSHPKYR---LELERRLPWLGIREKHATSGTSGGQESVASVS 372
            .:..:|.:|...:.::|   |.|      .|.:...::..:|..:..|:|||
Mouse   309 ATIYNPIIYVFMNRQFRNCILHL------FGKKVDDSSELSSTSKTEVSSVS 354

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rh5	NP_477096.1	7tmA_photoreceptors_insect	54..343	CDD:320207	75/316 (24%)
		TM helix 1	54..80	CDD:320207	7/31 (23%)
		TM helix 2	87..112	CDD:320207	6/27 (22%)
		TM helix 3	124..154	CDD:320207	7/35 (20%)
		TM helix 4	164..184	CDD:320207	5/19 (26%)
		TM helix 5	212..241	CDD:320207	4/30 (13%)
		TM helix 6	271..301	CDD:320207	6/29 (21%)
		TM helix 7	311..336	CDD:320207	8/24 (33%)
Opn1mw	NP_032132.1	Required for 11-cis-retinal regeneration. /evidence=ECO:0000250|UniProtKB:P04001	12..38		5/23 (22%)
		7tm_GPCRs	37..328	CDD:475119	77/320 (24%)
		TM helix 1	51..75	CDD:320209	7/23 (30%)
		TM helix 2	84..106	CDD:320209	6/23 (26%)
		TM helix 3	122..144	CDD:320209	6/24 (25%)
		TM helix 4	166..182	CDD:320209	5/15 (33%)
		TM helix 5	212..235	CDD:320209	3/22 (14%)
		TM helix 6	262..284	CDD:320209	5/24 (21%)
		TM helix 7	296..321	CDD:320209	8/24 (33%)