DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Rh5 and XB5957215

DIOPT Version :9

Sequence 1:	NP_001285859.1	Gene:	Rh5 / 34615	FlyBaseID:	FBgn0014019	Length:	382	Species:	Drosophila melanogaster
Sequence 2:	XP_031759018.1	Gene:	XB5957215 / 100485437	XenbaseID:	XB-GENE-5957216	Length:	582	Species:	Xenopus tropicalis

Alignment Length:	372	Identity:	102/372 - (27%)
Similarity:	183/372 - (49%)	Gaps:	54/372 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 GFREAP--IYYHAGFYIAFIVLMLSSIFGNGLVIWIFSTSKSLRTPSNLLILNLAIFDLFM-CTN 104
            |..:||  :.|..|.:|  :::....|.||.||::.|.::|.|||..|..|:||||.|..| .|.
Frog    18 GQLDAPAQVLYTIGSFI--LIIGFVGIIGNLLVLYAFYSNKKLRTAPNYFIMNLAISDFLMSATQ 80

  Fly   105 MPHYLINATVGYIVGGDLGCDIYALNGGISGMGASITNAFIAFDRYKTISNPI-----DGRLSYG 164
            .|...:::.....:.|::||::||..|.:.|:.:.:|...|:.:||..|:.|:     ..:....
Frog    81 APVCFLSSLHREWILGEIGCNVYAFCGALFGITSMMTLLAISVNRYIVITKPLQSIQWSSKKRTS 145

  Fly   165 QIVLLILFTWLWATPFSVLPLFQIWGRYQPEGFLTTCSFDYLTNTDENRLFVRTIFVWSYVIPMT 229
            |:::|:   |:::..:|:.||.. |..|.|||...:|::||:|:|..|:.:...:....:.||:.
Frog   146 QVIVLV---WMYSFMWSLAPLLG-WSSYVPEGLRISCTWDYVTSTTSNKSYTMMLCCCVFFIPLI 206

  Fly   230 MILVSYYKLFTHVRVHEKMLAEQAKKMNVKSLSANAN----ADNMSVELRIAKAALIIYMLFILA 290
            :|...|:.:|         ||.::...||:.|.:...    ...|..|.::||.|.:|.::::|:
Frog   207 IISHCYFFMF---------LAIRSTGRNVQKLGSYGRQSFLTPTMKNEWKMAKIAFVIIIVYVLS 262

  Fly   291 WTPYSVVALIGCFGEQQLITPFVSMLPCLACKSVSCLDPWVYATSHPKYRLELERRLPWLGI--- 352
            |:||:.|.||...|..:.:||:...:|.:..|:.:..:|.:|...|||||..:.:.:|.|..
Frog   263 WSPYACVTLIAWAGHGKSLTPYSKTVPAVIAKASAIYNPIIYGIIHPKYRETIHKTVPCLRFLIK 327

  Fly   353 -----------------------REKHATSGTSGGQESVAS-VSGDT 375
                                   |:|::...|....|:|:| |..||
Frog   328 EPKKDCFESSVRGSIYSRQSLVARKKNSCISTVSTAETVSSNVWDDT 374

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rh5	NP_001285859.1	7tm_4	60..>236	CDD:304433	53/181 (29%)
Rh5	NP_001285859.1	7tm_1	69..332	CDD:278431	78/272 (29%)
XB5957215	XP_031759018.1	7tmA_Melanopsin	28..315	CDD:320458	88/301 (29%)
		TM helix 1	30..54	CDD:320458	8/25 (32%)
		TM helix 2	63..85	CDD:320458	10/21 (48%)
		TM helix 3	101..123	CDD:320458	6/21 (29%)
		TM helix 4	146..162	CDD:320458	4/18 (22%)
		TM helix 5	190..213	CDD:320458	3/22 (14%)
		TM helix 6	249..271	CDD:320458	9/21 (43%)
		TM helix 7	283..308	CDD:320458	5/24 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9343
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000