DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hacd1 and Hacd3

DIOPT Version :9

Sequence 1:	NP_609534.1	Gene:	Hacd1 / 34614	FlyBaseID:	FBgn0032394	Length:	245	Species:	Drosophila melanogaster
Sequence 2:	NP_067320.2	Gene:	Hacd3 / 57874	MGIID:	1889341	Length:	362	Species:	Mus musculus

Alignment Length:	257	Identity:	75/257 - (29%)
Similarity:	121/257 - (47%)	Gaps:	32/257 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSAKAVSKSSKPGASKE--PSAVTKL---YLFAYNAGQVVGWSYILWQL-VNYYILQGPEFRAQV 59
            :.||...:.:|....:|  |..:|.|   |||.||..|::|:|:|...| |.::||....|..
Mouse   120 LRAKEEERLNKLRLEREGSPETLTNLKKGYLFMYNLVQLLGFSWIFVNLTVRFFILGKESFYD-- 182

  Fly    60 TLWEYTRLAVIIF--QNAAFVEILNASFGLVKSNPVVTGFQVFSRMMVVVGVVMATPTGKVSPGL 122
               .:..:|.:::  |..|.||.|||:.| |.|.||:.....|.....::.:|..|.....:..:
Mouse   183 ---TFHNVADMMYFCQMLALVETLNAAIG-VTSTPVLPALIQFLGRNFILFLVFGTMEEMQNKAV 243

  Fly   123 P-IALLAWAITEIIRYGYYALNIVKVVPHFVVFLRYTTFIVLYPIGVTGELLCFWWAQSYARENS 186
            . ....:|:..||.||.:|.|:.:.:....:.:||||.:|.|||:|...|.:....:.....|:.
Mouse   244 VFFVFYSWSAIEIFRYPFYMLSCIDMDWKVLTWLRYTMWIPLYPLGCLSEAVAVIQSIPVFNESG 308

  Fly   187 VWSVVMPN--KWNATFSYFGFLWIVMLGYIPIFPQLYL---HMFAQRRKILGGGSSGSPQKK 243
            .:|..:|.  |....||:|..:::|||     |..||:   |::.|||:..|       |||
Mouse   309 RFSFTLPYPVKMKVRFSFFLQVYLVML-----FLGLYINFRHLYKQRRRRYG-------QKK 358

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hacd1	NP_609534.1	PTPLA	73..232	CDD:282269	49/164 (30%)
Hacd3	NP_067320.2	p23_hB-ind1_like	8..115	CDD:107222
Hacd3	NP_067320.2	PTPLA	195..352	CDD:282269	48/162 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5198
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1458293at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.780