DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hacd1 and hacd3

DIOPT Version :9

Sequence 1:	NP_609534.1	Gene:	Hacd1 / 34614	FlyBaseID:	FBgn0032394	Length:	245	Species:	Drosophila melanogaster
Sequence 2:	NP_001038449.1	Gene:	hacd3 / 393441	ZFINID:	ZDB-GENE-040426-1200	Length:	359	Species:	Danio rerio

Alignment Length:	238	Identity:	64/238 - (26%)
Similarity:	113/238 - (47%)	Gaps:	22/238 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 KEP-SAVTKLYLFAYNAGQVVGWSYILWQL-VNYYILQGPEFRAQVTLWE--YTRLAVIIF-QNA 75
            |:| ..:.|.:||.||..|.:|:|:|...: |..:||      .|.:.::  :|...|:.| |..
Zfish   136 KDPFLGLKKGFLFMYNLVQFLGYSWIFVNMTVRLFIL------GQDSFYDTFHTIADVMYFCQML 194

  Fly    76 AFVEILNASFGLVKSNPVVTGFQVFSRMMVVVGVVMATPTGKVSPGLPIALLAWAITEIIRYGYY 140
            |.:|::|.:.||||:..:....||..|..::..:..:....:..|.:......|:..||.||.:|
Zfish   195 AIMEVINPAVGLVKTGVMPAFIQVMGRNFILFVIFGSLEDMQNKPVVFFVFYLWSTIEIFRYPFY 259

  Fly   141 ALNIVKVVPHFVVFLRYTTFIVLYPIGVTGELLCFWWAQSYARENSVWSVVMPNKWNATFSYFGF 205
            .|..:......:.:||||.::.|||:||..|.:....:.....|..:.|:.:|   .||.....|
Zfish   260 MLACIDTEWKLLTWLRYTIWMPLYPLGVLAEAVAVIQSIPIFDETKLLSIPLP---KATGLSLSF 321

  Fly   206 LWIVMLGYIPIFPQLYL---HMFAQRRKILGGGSSGSPQKKAN 245
            .:|:.|..:.:|..|::   |:|.||.:     ...:.::|||
Zfish   322 SYILQLYLVVMFLGLFINFRHLFKQRTR-----RFRTKKRKAN 359

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hacd1	NP_609534.1	PTPLA	73..232	CDD:282269	43/161 (27%)
hacd3	NP_001038449.1	p23_hB-ind1_like	6..113	CDD:107222
hacd3	NP_001038449.1	PTPLA	192..346	CDD:282269	41/156 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5198
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1458293at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	4	3.780