DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hacd1 and hacd2

DIOPT Version :9

Sequence 1:	NP_609534.1	Gene:	Hacd1 / 34614	FlyBaseID:	FBgn0032394	Length:	245	Species:	Drosophila melanogaster
Sequence 2:	NP_956155.1	Gene:	hacd2 / 334121	ZFINID:	ZDB-GENE-030131-6053	Length:	239	Species:	Danio rerio

Alignment Length:	232	Identity:	87/232 - (37%)
Similarity:	132/232 - (56%)	Gaps:	4/232 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SAKAVSKSSKPGASKEPSAVTKLYLFAYNAGQVVGWSYILWQLVNYYILQGPEFRAQVTLWEYTR 66
            ::|.....|.....|.|..:...||..||.....||..|...||..|:.:|    :...|:....
Zfish     3 TSKTAHSESGHKKKKGPGTLATAYLVIYNVIMTAGWLVIAVGLVRAYLARG----SYHGLYYSIE 63

  Fly    67 LAVIIFQNAAFVEILNASFGLVKSNPVVTGFQVFSRMMVVVGVVMATPTGKVSPGLPIALLAWAI 131
            ..:..||..|.:|||:.:.|:|.|:.|:|||||.||:.:...|..:....:....:.:.::||.:
Zfish    64 KPLKFFQTGALLEILHCAVGIVPSSVVLTGFQVMSRVFLTWAVTHSVREVQSEDSVLLFVVAWTV 128

  Fly   132 TEIIRYGYYALNIVKVVPHFVVFLRYTTFIVLYPIGVTGELLCFWWAQSYARENSVWSVVMPNKW 196
            ||||||.:|..:::..:|:.:.:.|||.||||||:||.||||..:.|..|.::..::|:.:|||:
Zfish   129 TEIIRYSFYTFSLLNHLPYLIKWARYTFFIVLYPMGVMGELLTIYAALPYVQKAGLYSITLPNKY 193

  Fly   197 NATFSYFGFLWIVMLGYIPIFPQLYLHMFAQRRKILG 233
            |.:|.|..||..||:.|||:|||||.||..||:|:||
Zfish   194 NFSFDYHTFLIFVMISYIPLFPQLYFHMMRQRKKVLG 230

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hacd1	NP_609534.1	PTPLA	73..232	CDD:282269	68/158 (43%)
hacd2	NP_956155.1	PTPLA	70..229	CDD:282269	68/158 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170586360
Domainoid	1	1.000	151	1.000	Domainoid score	I4322
eggNOG	1	0.900	-	-		E1_COG5198
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H23409
Inparanoid	1	1.050	168	1.000	Inparanoid score	I4128
OMA	1	1.010	-	-		QHG54207
OrthoDB	1	1.010	-	-		D1458293at2759
OrthoFinder	1	1.000	-	-		FOG0001899
OrthoInspector	1	1.000	-	-		otm24908
orthoMCL	1	0.900	-	-		OOG6_101538
Panther	1	1.100	-	-	LDO	PTHR11035
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R545
SonicParanoid	1	1.000	-	-		X1253
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800