DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hacd1 and Hacd1

DIOPT Version :9

Sequence 1:	NP_609534.1	Gene:	Hacd1 / 34614	FlyBaseID:	FBgn0032394	Length:	245	Species:	Drosophila melanogaster
Sequence 2:	NP_038963.3	Gene:	Hacd1 / 30963	MGIID:	1353592	Length:	248	Species:	Mus musculus

Alignment Length:	233	Identity:	79/233 - (33%)
Similarity:	134/233 - (57%)	Gaps:	4/233 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SAKAVSKSSKPGASKEPSAVTKLYLFAYNAGQVVGWSYILWQLVNYYILQGPEFRAQVTLWEYTR 66
            :::|..:....|..:....:...:|..||.....||..:...:|.:|:.:|    ....|::..:
Mouse    12 ASEASDEKEAAGKRRRLGLLATAWLTFYNIAMTAGWLVLAIAMVRFYMEKG----THRGLYKSIQ 72

  Fly    67 LAVIIFQNAAFVEILNASFGLVKSNPVVTGFQVFSRMMVVVGVVMATPTGKVSPGLPIALLAWAI 131
            ..:..||..|.:|:::...|:|.::.:|||.||.||:.:|..:..:....:....:.:.|::|.:
Mouse    73 KTLKFFQTFALLEVVHCLIGIVPTSVLVTGVQVSSRIFMVWLITHSIKPIQNEESVVLFLVSWTV 137

  Fly   132 TEIIRYGYYALNIVKVVPHFVVFLRYTTFIVLYPIGVTGELLCFWWAQSYARENSVWSVVMPNKW 196
            |||.||.:|..:::..:|||:.:.||..||:|||:||.||||..:.|..|.:::.::||.:|||:
Mouse   138 TEITRYSFYTFSLLDHLPHFIKWARYNLFIILYPVGVAGELLTIYAALPYVKKSGMFSVRLPNKY 202

  Fly   197 NATFSYFGFLWIVMLGYIPIFPQLYLHMFAQRRKILGG 234
            |.:|.|:.||.|.|..|||:|||||.||..||||:|.|
Mouse   203 NVSFDYYYFLLITMASYIPLFPQLYFHMLRQRRKVLHG 240

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hacd1	NP_609534.1	PTPLA	73..232	CDD:282269	65/158 (41%)
Hacd1	NP_038963.3	PTPLA	79..238	CDD:282269	62/158 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167841879
Domainoid	1	1.000	153	1.000	Domainoid score	I4280
eggNOG	1	0.900	-	-		E1_COG5198
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	173	1.000	Inparanoid score	I4074
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54207
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001899
OrthoInspector	1	1.000	-	-		otm43169
orthoMCL	1	0.900	-	-		OOG6_101538
Panther	1	1.100	-	-	O	PTHR11035
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R545
SonicParanoid	1	1.000	-	-		X1253
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.790