DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hacd1 and hpo-8

DIOPT Version :9

Sequence 1:	NP_609534.1	Gene:	Hacd1 / 34614	FlyBaseID:	FBgn0032394	Length:	245	Species:	Drosophila melanogaster
Sequence 2:	NP_504740.2	Gene:	hpo-8 / 188513	WormBaseID:	WBGene00020517	Length:	218	Species:	Caenorhabditis elegans

Alignment Length:	217	Identity:	94/217 - (43%)
Similarity:	139/217 - (64%)	Gaps:	13/217 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 YLFAYNAGQVVGWSYILWQ----LVNYYILQGPEFRAQVTLWEYTRLAVIIFQNAAFVEILNASF 85
            ||.|||..|::|||.||.:    |.|.  |..|:      |:|.....:.|||.||.:|:::|..
Worm     6 YLVAYNVLQILGWSAILVKTVLGLANG--LTWPQ------LYESVEFELKIFQTAAILEVIHAIV 62

  Fly    86 GLVKSNPVVTGFQVFSRMMVVVGVVMATPTGKVSPGLPIALLAWAITEIIRYGYYALNIVK-VVP 149
            |||:|....|..||.||:::|..::....|.:.|.|:|:.|:||::||:|||.:|||:::| .:|
Worm    63 GLVRSPVGTTAMQVTSRVVLVWPILHLCSTARFSIGVPLLLVAWSVTEVIRYSFYALSVLKQPIP 127

  Fly   150 HFVVFLRYTTFIVLYPIGVTGELLCFWWAQSYARENSVWSVVMPNKWNATFSYFGFLWIVMLGYI 214
            :|:::||||.|.||||:||:||||..:.:.:...|..:.::.|||:.|...|::..|.|..|.||
Worm   128 YFLLYLRYTLFYVLYPMGVSGELLTLFASLNEVDEKKILTLEMPNRLNMGISFWWVLIIAALSYI 192

  Fly   215 PIFPQLYLHMFAQRRKILGGGS 236
            |.|||||.:|..||:|||||||
Worm   193 PGFPQLYFYMIGQRKKILGGGS 214

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hacd1	NP_609534.1	PTPLA	73..232	CDD:282269	69/159 (43%)
hpo-8	NP_504740.2	PTPLA	50..210	CDD:282269	69/159 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162183
Domainoid	1	1.000	145	1.000	Domainoid score	I2834
eggNOG	1	0.900	-	-		E1_COG5198
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H23409
Inparanoid	1	1.050	170	1.000	Inparanoid score	I2760
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54207
OrthoDB	1	1.010	-	-		D1458293at2759
OrthoFinder	1	1.000	-	-		FOG0001899
OrthoInspector	1	1.000	-	-		oto17715
orthoMCL	1	0.900	-	-		OOG6_101538
Panther	1	1.100	-	-	LDO	PTHR11035
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R545
SonicParanoid	1	1.000	-	-		X1253
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	16	15.840