Protein Alignment Nfs1 and NFS1

DIOPT Version :10

• Sequence 1: NP_609533.1
• Gene: Nfs1 / 34613
• FlyBaseID: FBgn0032393
• Length: 462
• Species: Drosophila melanogaster
• Sequence 2: NP_066923.3
• Gene: NFS1 / 9054
• HGNCID: 15910
• Length: 457
• Species: Homo sapiens
• Alignment Length: 445
• Identity: 321/445 - (72%)
• Similarity: 380/445 - (85%)
• Gaps: 11/445 - (2%)

  Fly    29 ATSSRTAAKPAATSKEFR----ERQVRFNIKNEQTEG-------RPLYLDAQATTPMDPRVLDAM 82
            |.::....||||.::..|    :|..:..:..:....       ||||:|.|||||:||||||||
Human    13 AVTAAPGPKPAAPTRGLRLRVGDRAPQSAVPADTAAAPEVGPVLRPLYMDVQATTPLDPRVLDAM 77

  Fly    83 LPYLTNFYGNPHSRTHAYGWETESAVEKAREQVATLIGADPKEIIFTSGATESNNIAVKGVARFY 147
            ||||.|:||||||||||||||:|:|:|:||:|||:||||||:|||||||||||||||:|||||||
Human    78 LPYLINYYGNPHSRTHAYGWESEAAMERARQQVASLIGADPREIIFTSGATESNNIAIKGVARFY 142

  Fly   148 GTKKRHVITTQTEHKCVLDSCRALENEGFKVTYLPVLANGLIDLQQLEETITSETSLVSIMTVNN 212
            .::|:|:|||||||||||||||:||.|||:||||||..:|:|||::||..|..:|||||:|||||
Human   143 RSRKKHLITTQTEHKCVLDSCRSLEAEGFQVTYLPVQKSGIIDLKELEAAIQPDTSLVSVMTVNN 207

  Fly   213 EIGVRQPVDEIGKLCRSRRVFFHTDAAQAVGKVPLDVNAMNIDLMSISGHKIYGPKGVGALYVRR 277
            ||||:||:.|||::|.||:|:|||||||||||:|||||.|.|||||||||||||||||||:|:||
Human   208 EIGVKQPIAEIGRICSSRKVYFHTDAAQAVGKIPLDVNDMKIDLMSISGHKIYGPKGVGAIYIRR 272

  Fly   278 RPRVRLEPIQSGGGQERGLRSGTVPAPLAVGLGAAAELSLREMDYDKKWVDFLSNRLLDRISSAL 342
            |||||:|.:|||||||||:||||||.||.||||||.|::.:||:||.|.:..||.||:..|..:|
Human   273 RPRVRVEALQSGGGQERGMRSGTVPTPLVVGLGAACEVAQQEMEYDHKRISKLSERLIQNIMKSL 337

  Fly   343 PHVIRNGDAKATYNGCLNLSFAYVEGESLLMALKDVALSSGSACTSASLEPSYVLRAIGTDEDLA 407
            |.|:.|||.|..|.||:||||||||||||||||||||||||||||||||||||||||||||||||
Human   338 PDVVMNGDPKHHYPGCINLSFAYVEGESLLMALKDVALSSGSACTSASLEPSYVLRAIGTDEDLA 402

  Fly   408 HSSIRFGIGRFTTVEEVDYTADKCIKHVERLREMSPLWEMVQEGIDLKTIQWSQH 462
            |||||||||||||.||||||.:|||:||:|||||||||||||:|||||:|:|:||
Human   403 HSSIRFGIGRFTTEEEVDYTVEKCIQHVKRLREMSPLWEMVQDGIDLKSIKWTQH 457

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nfs1	NP_609533.1	AAT_I	63..462	CDD:450240	311/398 (78%)
NFS1	NP_066923.3	PRK14012	58..457	CDD:184450	311/398 (78%)