Protein Alignment escl and eed

DIOPT Version :10

• Sequence 1: NP_723702.1
• Gene: escl / 34611
• FlyBaseID: FBgn0032391
• Length: 462
• Species: Drosophila melanogaster
• Sequence 2: NP_001017325.1
• Gene: eed / 550079
• XenbaseID: XB-GENE-491480
• Length: 438
• Species: Xenopus tropicalis
• Alignment Length: 457
• Identity: 243/457 - (53%)
• Similarity: 311/457 - (68%)
• Gaps: 41/457 - (8%)

  Fly    15 EPPAEDESTDHSPAEAVLSNNSSSVCNVVEPDDEHEVNSVDREDTASLFSTTTT------TTRSK 73
            |.||:.:.         ||::.:|         ..|::..:.:||.|:.|.|.|      |..:.
 Frog    12 EMPAKKQK---------LSSDENS---------NPELSGDENDDTVSIESGTNTERPDTPTNAAN 58

  Fly    74 SPNTRKLNRLCRRIKAPKMVQPLYKYS----SHVREDHNHQIFGVQFNPFLDRGQPQVFATVGKD 134
            :|..:...:  .:.|:.|.     |||    :.::||||..:||||||.....|.|.||||||.:
 Frog    59 APGRKGWGK--GKWKSKKC-----KYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSN 116

  Fly   135 RVSIYECERSTGQESCEGIRLLQVYADPDTDESFYTCAWSYDSVTGDPVLAAAGYRGVIRIFNPV 199
            ||::||| ...|:     |||||.|.|.|.||:||||||:|||.|..|:||.||.||:|||.||:
 Frog   117 RVTLYEC-HPQGE-----IRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPI 175

  Fly   200 KHQCSKNYIGHGHAINELKFHPTRPQLLLSGSKDHSLRLWNIQSDVCVAVFGGVEGHRDEVLSVD 264
            ..||.|:|:|||:|||||||||..|.||||.||||:|||||||:|..||:|||||||||||||.|
 Frog   176 TMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSAD 240

  Fly   265 FDLRGDRIMSSGMDHSLKLWRLDKPDIKEAIELSSGFSPNKNTGPFPTIKEHFPDFSTRDIHRNY 329
            :||.|::|||.||||||||||::...:|.||..|..::|||...||.:.|.||||||||||||||
 Frog   241 YDLLGEKIMSCGMDHSLKLWRINSLRMKTAIRESYEYNPNKTNRPFVSQKIHFPDFSTRDIHRNY 305

  Fly   330 VDCVQWFGDFVFSKSCENSIVCWKPGKLSESWHEIKPQESATTVLHHFDYKMCEIWFVRFAFNAW 394
            ||||:|.||.:.||||||:||||||||:.:...:||..||..|:|..|||..|:||::||:.:.|
 Frog   306 VDCVRWLGDLILSKSCENAIVCWKPGKMEDDIDKIKASESNVTILGRFDYSQCDIWYMRFSMDFW 370

  Fly   395 QKILALGNQLGTTFVWELDCNDPNLTKCSQLVHPKSNSTIRQTSFSKDGSILVCVCDDSTVWRWD 459
            ||:||||||:|..:||:|:..||:..||:.|.:||..|.|||||||:|.||||.||||:|:||||
 Frog   371 QKMLALGNQVGKLYVWDLEVEDPHKAKCTTLTYPKCASAIRQTSFSRDSSILVAVCDDATIWRWD 435

  Fly   460 RV 461
            |:
 Frog   436 RL 437

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
escl	NP_723702.1	WD40	102..460	CDD:441893	221/357 (62%)
		WD40 repeat	111..158	CDD:293791	24/46 (52%)
		WD40 repeat	169..209	CDD:293791	25/39 (64%)
		WD40 repeat	214..251	CDD:293791	27/36 (75%)
		WD40 repeat	261..323	CDD:293791	35/61 (57%)
		WD40 repeat	330..378	CDD:293791	27/47 (57%)
		WD40 repeat	386..426	CDD:293791	19/39 (49%)
		WD40 repeat	434..458	CDD:293791	18/23 (78%)
eed	NP_001017325.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..70		15/77 (19%)
		WD 1	88..131		24/48 (50%)
		WD40 repeat	93..137	CDD:293791	26/49 (53%)
		WD40	<106..436	CDD:441893	210/335 (63%)
		WD 2	139..182		27/42 (64%)
		WD40 repeat	145..185	CDD:293791	25/39 (64%)
		WD 3	185..225		30/39 (77%)
		WD40 repeat	190..227	CDD:293791	27/36 (75%)
		WD 4	231..270		26/38 (68%)
		WD40 repeat	237..299	CDD:293791	35/61 (57%)
		WD 5	301..338		26/36 (72%)
		WD40 repeat	306..354	CDD:293791	27/47 (57%)
		WD 6	356..396		20/39 (51%)
		WD40 repeat	362..402	CDD:293791	19/39 (49%)
		WD 7	405..438		24/33 (73%)
		WD40 repeat	410..434	CDD:293791	18/23 (78%)