Protein Alignment escl and esc

DIOPT Version :10

• Sequence 1: NP_723702.1
• Gene: escl / 34611
• FlyBaseID: FBgn0032391
• Length: 462
• Species: Drosophila melanogaster
• Sequence 2: NP_477431.1
• Gene: esc / 34595
• FlyBaseID: FBgn0000588
• Length: 425
• Species: Drosophila melanogaster
• Alignment Length: 428
• Identity: 250/428 - (58%)
• Similarity: 319/428 - (74%)
• Gaps: 12/428 - (2%)

  Fly    35 NSSSVCNVVEPDDEHEVNSVDREDTASLFSTTTTTTRSKSP--NTRKLNRLCRRIKAPKMVQPLY 97
            :|..|.|..||::..|    ...|.::.::|.:||:|||||  :||...|..|..|:....:..|
  Fly     2 SSDKVKNGNEPEESEE----SCGDESASYTTNSTTSRSKSPSSSTRSKRRGRRSTKSKPKSRAAY 62

  Fly    98 KYSSHVREDHNHQIFGVQFNPFLDRGQPQVFATVGKDRVSIYECERSTGQESCEGIRLLQVYADP 162
            ||.:||:|:|...||||.||..|.:.:||||||.|.:||::|||.|.      .|::||..||||
  Fly    63 KYDTHVKENHGANIFGVAFNTLLGKDEPQVFATAGSNRVTVYECPRQ------GGMQLLHCYADP 121

  Fly   163 DTDESFYTCAWSYDSVTGDPVLAAAGYRGVIRIFNPVKHQCSKNYIGHGHAINELKFHPTRPQLL 227
            |.||.|||||||||..|..|:|||||||||||:.:..:::...||||||.|||||||||.:.|||
  Fly   122 DPDEVFYTCAWSYDLKTSSPLLAAAGYRGVIRVIDVEQNEAVGNYIGHGQAINELKFHPHKLQLL 186

  Fly   228 LSGSKDHSLRLWNIQSDVCVAVFGGVEGHRDEVLSVDFDLRGDRIMSSGMDHSLKLWRLDKPDIK 292
            |||||||::|||||||.||:|:.||||||||||||:||::|||||:|||||||||||.|:.|:..
  Fly   187 LSGSKDHAIRLWNIQSHVCIAILGGVEGHRDEVLSIDFNMRGDRIVSSGMDHSLKLWCLNTPEFH 251

  Fly   293 EAIELSSGFSPNKNTGPFPTIKEHFPDFSTRDIHRNYVDCVQWFGDFVFSKSCENSIVCWKPGKL 357
            ..||||:.||..|:|.||||:.:||||||||||||||||||||||:||.||||||:|||||||:|
  Fly   252 HKIELSNTFSQEKSTLPFPTVTKHFPDFSTRDIHRNYVDCVQWFGNFVLSKSCENAIVCWKPGQL 316

  Fly   358 SESWHEIKPQESATTVLHHFDYKMCEIWFVRFAFNAWQKILALGNQLGTTFVWELDCNDPNLTKC 422
            .:|:.::||.:|:.|::..|:|..||||||||.||.|||::|||||.|..:|||||.:||.....
  Fly   317 HQSFEQVKPSDSSCTIIAEFEYDECEIWFVRFGFNPWQKVIALGNQQGKVYVWELDPSDPEGAHM 381

  Fly   423 SQLVHPKSNSTIRQTSFSKDGSILVCVCDDSTVWRWDR 460
            :.|.:.:|.:|:||.:||:|.|:||.||||:|||||:|
  Fly   382 TTLHNSRSVATVRQIAFSRDASVLVYVCDDATVWRWNR 419

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
escl	NP_723702.1	WD40	102..460	CDD:441893	226/357 (63%)
		WD40 repeat	111..158	CDD:293791	23/46 (50%)
		WD40 repeat	169..209	CDD:293791	23/39 (59%)
		WD40 repeat	214..251	CDD:293791	28/36 (78%)
		WD40 repeat	261..323	CDD:293791	40/61 (66%)
		WD40 repeat	330..378	CDD:293791	29/47 (62%)
		WD40 repeat	386..426	CDD:293791	22/39 (56%)
		WD40 repeat	434..458	CDD:293791	15/23 (65%)
esc	NP_477431.1	WD40	72..420	CDD:441893	224/354 (63%)
		WD40 repeat	76..122	CDD:293791	26/51 (51%)
		WD40 repeat	128..168	CDD:293791	23/39 (59%)
		WD40 repeat	173..210	CDD:293791	28/36 (78%)
		WD40 repeat	220..282	CDD:293791	40/61 (66%)
		WD40 repeat	289..337	CDD:293791	29/47 (62%)
		WD40 repeat	345..386	CDD:293791	23/40 (58%)
		WD40 repeat	393..417	CDD:293791	15/23 (65%)