| Sequence 1: | NP_001285857.1 | Gene: | escl / 34611 | FlyBaseID: | FBgn0032391 | Length: | 462 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_068676.1 | Gene: | Eed / 13626 | MGIID: | 95286 | Length: | 441 | Species: | Mus musculus |
| Alignment Length: | 476 | Identity: | 245/476 - (51%) |
|---|---|---|---|
| Similarity: | 315/476 - (66%) | Gaps: | 51/476 - (10%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 1 MTETNPSEISPPSEEPPAEDESTDHSPAEAVLSNNSSSVCNVVEPDDEHEVNSVDREDTASLFST 65
Fly 66 TTT---TTRSKSPNTRKLNRLCRRIKAP--------KMVQPLYKYS----SHVREDHNHQIFGVQ 115
Fly 116 FNPFLDRGQPQVFATVGKDRVSIYECERSTGQESCEGIRLLQVYADPDTDESFYTCAWSYDSVTG 180
Fly 181 DPVLAAAGYRGVIRIFNPVKHQCSKNYIGHGHAINELKFHPTRPQLLLSGSKDHSLRLWNIQSDV 245
Fly 246 CVAVFGGVEGHRDEVLSVDFDLRGDRIMSSGMDHSLKLWRLDKPDIKEAIELSSGFSPNKNTGPF 310
Fly 311 PTIKEHFPDFSTRDIHRNYVDCVQWFGDFVFSKSCENSIVCWKPGKLSESWHEIKPQESATTVLH 375
Fly 376 HFDYKMCEIWFVRFAFNAWQKILALGNQLGTTFVWELDCNDPNLTKCSQLVHPKSNSTIRQTSFS 440
Fly 441 KDGSILVCVCDDSTVWRWDRV 461 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| escl | NP_001285857.1 | WD40 | 96..459 | CDD:225201 | 221/366 (60%) |
| WD40 | 107..352 | CDD:295369 | 158/244 (65%) | ||
| WD40 repeat | 111..158 | CDD:293791 | 25/46 (54%) | ||
| WD40 repeat | 169..209 | CDD:293791 | 25/39 (64%) | ||
| WD40 repeat | 214..251 | CDD:293791 | 27/36 (75%) | ||
| WD40 | 253..>459 | CDD:295369 | 123/205 (60%) | ||
| WD40 repeat | 261..323 | CDD:293791 | 34/61 (56%) | ||
| WD40 repeat | 330..378 | CDD:293791 | 28/47 (60%) | ||
| WD40 repeat | 386..426 | CDD:293791 | 19/39 (49%) | ||
| WD40 repeat | 434..458 | CDD:293791 | 16/23 (70%) | ||
| Eed | NP_068676.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..72 | 20/100 (20%) | |
| Interaction with EZH2 | 81..441 | 222/366 (61%) | |||
| WD40 repeat | 96..140 | CDD:293791 | 27/49 (55%) | ||
| WD40 repeat | 148..188 | CDD:293791 | 25/39 (64%) | ||
| WD40 | 150..438 | CDD:421866 | 180/287 (63%) | ||
| WD40 repeat | 193..230 | CDD:293791 | 27/36 (75%) | ||
| WD40 repeat | 240..302 | CDD:293791 | 34/61 (56%) | ||
| WD40 repeat | 309..357 | CDD:293791 | 28/47 (60%) | ||
| WD40 repeat | 365..405 | CDD:293791 | 19/39 (49%) | ||
| WD40 repeat | 413..437 | CDD:293791 | 16/23 (70%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C167831198 | |
| Domainoid | 1 | 1.000 | 236 | 1.000 | Domainoid score | I2333 |
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 1 | 1.000 | - | - | H2814 | |
| Inparanoid | 1 | 1.050 | 488 | 1.000 | Inparanoid score | I1406 |
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 1 | 1.010 | - | - | QHG59795 | |
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 1 | 1.000 | - | - | FOG0005723 | |
| OrthoInspector | 1 | 1.000 | - | - | otm43279 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_102885 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR10253 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R2640 |
| SonicParanoid | 1 | 1.000 | - | - | X4715 | |
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 14 | 13.930 | |||||