DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment zuc and PGS1

DIOPT Version :9

Sequence 1:	NP_609530.1	Gene:	zuc / 34609	FlyBaseID:	FBgn0261266	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	XP_011523789.1	Gene:	PGS1 / 9489	HGNCID:	30029	Length:	646	Species:	Homo sapiens

Alignment Length:	193	Identity:	35/193 - (18%)
Similarity:	65/193 - (33%)	Gaps:	86/193 - (44%)

- Green bases have known domain annotations that are detailed below.

  Fly    78 PQVS--PCC----------------------NTHCS-LRNVAKIVE----QIDRAVYSIDLA-IY 112
            |||:  |||                      ::|.. |.:.|:..|    ||..|...:.:| :|
Human   153 PQVTSPPCCLCPEGVHRFQWIRNLVPEFGVSSSHVRVLSSPAEFFELMKGQIRVAKRRVVMASLY 217

  Fly   113 TFTSLF---LADSIKRALQRGVIIRIISDGE----MVYSKGS---------------------QI 149
            ..|...   |.|.::..|::.:..:..|:.:    :.:::||                     ::
Human   218 LGTGPLEQELVDCLESTLEKSLQAKFPSNLKVSILLDFTRGSRGRKNSRTMLLPLLRRFPEQVRV 282

  Fly   150 SM--------LAQLGVPVRVPITTNLMHNKFCIIDGFERVEEIRLLRKLKFMRPCYSIVISGS 204
            |:        |.:|.:|.|...|..|.|.|..:.|.                    |:::||:
Human   283 SLFHTPHLRGLLRLLIPERFNETIGLQHIKVYLFDN--------------------SVILSGA 325

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zuc	NP_609530.1	PLDc_SF	87..239	CDD:301585	29/160 (18%)
zuc	NP_609530.1	PLDc_2	96..239	CDD:289836	26/150 (17%)
PGS1	XP_011523789.1	PLDc_PGS1_euk_1	186..359	CDD:197233	29/160 (18%)
		PLDc_2	203..355	CDD:289836	25/143 (17%)
		PLDc_PGS1_euk_2	439..598	CDD:197235
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1502
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900