DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment zuc and pld6

DIOPT Version :9

Sequence 1:	NP_609530.1	Gene:	zuc / 34609	FlyBaseID:	FBgn0261266	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	NP_001082883.1	Gene:	pld6 / 567338	ZFINID:	ZDB-GENE-030131-3825	Length:	227	Species:	Danio rerio

Alignment Length:	242	Identity:	68/242 - (28%)
Similarity:	123/242 - (50%)	Gaps:	41/242 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 IMKQIRDYPIVSTISI-AVSTVLASEVIWKLVQCSRSKREKASRVHEVIIFNELGEICAAVHMRN 70
            :.||:....::..:.: .|:.||..|  | |...:|..|:....:.||:.|.. .::|.. |:..
Zfish     3 VFKQMSFKELMKVLGLGTVAFVLGVE--W-LNWLTRRLRDSRGPLKEVLFFPS-PQVCVE-HLFT 62

  Fly    71 SSMGSQKPQVSPCCNTHCSL-----RNVAKIVEQIDRAVYSIDLAIYTFTSLFLADSIKRALQRG 130
            |.      :..||.   |.|     .:.::::|.:..|..|:::.|::|:::.::.:|....:||
Zfish    63 SH------RSFPCA---CPLPHGIQTSFSRLLEHLLSARTSLEMCIFSFSNMEMSRAILLLHKRG 118

  Fly   131 VIIRIISDGEMVYSKGSQISMLAQLGVPVRVPITTNL-MHNKFCIIDGFERVEEIRLLRKLKFMR 194
            |::|:::|.:.:...||||..|.:.|:.||..:::.: ||:||.::||          |||
Zfish   119 VVVRVVTDRDYMTITGSQIGALRKAGISVRHEMSSAVHMHHKFALVDG----------RKL---- 169

  Fly   195 PCYSIVISGSVNWTALGLGGNWENCIITADDKLTATFQAEFQRMWRA 241
                  ||||:|||...:..|.||.|||.:.:|...||.||.::|.|
Zfish   170 ------ISGSLNWTLTAVQSNKENVIITEEPELVRPFQQEFLKLWEA 210

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zuc	NP_609530.1	PLDc_SF	87..239	CDD:301585	48/157 (31%)
zuc	NP_609530.1	PLDc_2	96..239	CDD:289836	46/143 (32%)
pld6	NP_001082883.1	PLDc_vPLD6_like	71..208	CDD:197268	48/156 (31%)
pld6	NP_001082883.1	PLDc_2	84..208	CDD:289836	46/143 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170591948
Domainoid	1	1.000	81	1.000	Domainoid score	I8492
eggNOG	1	0.900	-	-		E1_COG1502
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	86	1.000	Inparanoid score	I5146
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1489926at2759
OrthoFinder	1	1.000	-	-		FOG0006595
OrthoInspector	1	1.000	-	-		oto40600
orthoMCL	1	0.900	-	-		OOG6_103738
Panther	1	1.100	-	-	LDO	PTHR43856
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4839
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	13	12.790