DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment zuc and Pld6

DIOPT Version :9

Sequence 1:	NP_609530.1	Gene:	zuc / 34609	FlyBaseID:	FBgn0261266	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	XP_220517.1	Gene:	Pld6 / 287366	RGDID:	1311987	Length:	222	Species:	Rattus norvegicus

Alignment Length:	226	Identity:	60/226 - (26%)
Similarity:	103/226 - (45%)	Gaps:	35/226 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 LASEVI-----WKLVQCSRSKREKASRVHEVIIFNELGEICAAVHMRNSSMGSQKPQVSPCCNTH 87
            ||.|.:     | |:...|.:||        ::|......|....::...:........||...|
  Rat    18 LALEALPWLMRW-LLAGRRPRRE--------VLFFPSQVTCTEALLQAPGLPPGPSSGCPCSLPH 73

  Fly    88 CSLRNVAKIVEQIDRAVYSIDLAIYTFTSLFLADSIKRALQRGVIIRIISDGEMVYSKGSQISML 152
             |..::::::..:..|..|::|.::.|:|..|..:::...||||.:|:|:|.:.:...||||.:|
  Rat    74 -SESSLSRLLRALLAARSSLELCLFAFSSPQLGRAVQLLHQRGVRVRVITDCDYMALNGSQIGLL 137

  Fly   153 AQLGVPVRVPITTNLMHNKFCIIDGFERVEEIRLLRKLKFMRPCYSIVISGSVNWTALGLGGNWE 217
            .:.|:.||.......||:||.|:|                    ..::|:||:|||...:..|.|
  Rat   138 RKAGIQVRHDQDLGYMHHKFAIVD--------------------KKVLITGSLNWTTQAIQNNRE 182

  Fly   218 NCIITADDKLTATFQAEFQRMWRAFAKTEGS 248
            |.:|..|.:....|..||:|:|..|..|:.|
  Rat   183 NVLIMEDTEYVRLFLEEFERIWEEFDPTKYS 213

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zuc	NP_609530.1	PLDc_SF	87..239	CDD:301585	44/151 (29%)
zuc	NP_609530.1	PLDc_2	96..239	CDD:289836	42/142 (30%)
Pld6	XP_220517.1	PLDc_vPLD6_like	93..204	CDD:197268	40/130 (31%)
Pld6	XP_220517.1	PLDc_2	94..204	CDD:289836	40/129 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166350275
Domainoid	1	1.000	76	1.000	Domainoid score	I8766
eggNOG	1	0.900	-	-		E1_COG1502
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	84	1.000	Inparanoid score	I5080
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1489926at2759
OrthoFinder	1	1.000	-	-		FOG0006595
OrthoInspector	1	1.000	-	-		oto95723
orthoMCL	1	0.900	-	-		OOG6_103738
Panther	1	1.100	-	-	LDO	PTHR43856
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.760