DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment zuc and Pld6

DIOPT Version :9

Sequence 1:	NP_609530.1	Gene:	zuc / 34609	FlyBaseID:	FBgn0261266	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	NP_001277212.1	Gene:	Pld6 / 194908	MGIID:	2687283	Length:	221	Species:	Mus musculus

Alignment Length:	171	Identity:	51/171 - (29%)
Similarity:	86/171 - (50%)	Gaps:	21/171 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    78 PQVSPCCNTHCSLRNVAKIVEQIDRAVYSIDLAIYTFTSLFLADSIKRALQRGVIIRIISDGEMV 142
            |...||...| |..::::::..:..|..|::|.::.|:|..|..:::...||||.:|:|:|.:.:
Mouse    63 PSGCPCSLPH-SESSLSRLLRALLAARSSLELCLFAFSSPQLGRAVQLLHQRGVRVRVITDCDYM 126

  Fly   143 YSKGSQISMLAQLGVPVRVPITTNLMHNKFCIIDGFERVEEIRLLRKLKFMRPCYSIVISGSVNW 207
            ...||||.:|.:.|:.||.......||:||.|:|                    ..::|:||:||
Mouse   127 ALNGSQIGLLRKAGIQVRHDQDLGYMHHKFAIVD--------------------KKVLITGSLNW 171

  Fly   208 TALGLGGNWENCIITADDKLTATFQAEFQRMWRAFAKTEGS 248
            |...:..|.||.:|..|.:....|..||:|:|..|..|:.|
Mouse   172 TTQAIQNNRENVLIMEDTEYVRLFLEEFERIWEEFDPTKYS 212

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zuc	NP_609530.1	PLDc_SF	87..239	CDD:301585	44/151 (29%)
zuc	NP_609530.1	PLDc_2	96..239	CDD:289836	42/142 (30%)
Pld6	NP_001277212.1	Required for mitochondrial localization	1..38
		PLDc_vPLD6_like	92..203	CDD:197268	40/130 (31%)
		PLDc_2	93..203	CDD:289836	40/129 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846743
Domainoid	1	1.000	76	1.000	Domainoid score	I8974
eggNOG	1	0.900	-	-		E1_COG1502
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	85	1.000	Inparanoid score	I5159
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006595
OrthoInspector	1	1.000	-	-		oto92155
orthoMCL	1	0.900	-	-		OOG6_103738
Panther	1	1.100	-	-	LDO	PTHR43856
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4839
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.780