DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment zuc and Pld2

DIOPT Version :9

Sequence 1:	NP_609530.1	Gene:	zuc / 34609	FlyBaseID:	FBgn0261266	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	NP_001289404.1	Gene:	Pld2 / 18806	MGIID:	892877	Length:	944	Species:	Mus musculus

Alignment Length:	201	Identity:	41/201 - (20%)
Similarity:	79/201 - (39%)	Gaps:	57/201 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 FNELGEIC----AAVHMRNSSMGSQ-KPQVSPC-CNTHCSLRNVAKIVEQIDRAVYSIDLAIYTF 114
            |..|..:|    :.:|...::||:. :..:|.| ..||..|..            :.|...||..
Mouse   715 FFSLRTLCRGEHSILHRLKAAMGTAWRDYMSICGLRTHGELGG------------HPISELIYIH 767

  Fly   115 TSLFLADSIKRALQRGVII--RIISDGEMVYSKGSQISMLAQLGVPVRVPITTNLMHNKFCIIDG 177
            :.:.:||      .|.|||  ..|:|..::..:.|::::|.:         .|.:..:   ::||
Mouse   768 SKMLIAD------DRTVIIGSANINDRSLLGKRDSELAILIK---------DTEMEPS---LMDG 814

  Fly   178 FERVEEIRLLRKLKFMRPCYSIVISGSVNWTALGLGGNWENCIITADDKLTATFQAEFQRMWRAF 242
            .| .:..|....|:  :.|:|::: |:..|..|.|...      ..||         |.::|:..
Mouse   815 VE-YQAGRFALSLR--KHCFSVIL-GANTWPDLDLRDP------VCDD---------FFQLWQET 860

  Fly   243 AKTEGS 248
            |:...:
Mouse   861 AENNAT 866

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zuc	NP_609530.1	PLDc_SF	87..239	CDD:301585	30/153 (20%)
zuc	NP_609530.1	PLDc_2	96..239	CDD:289836	28/144 (19%)
Pld2	NP_001289404.1	PX_domain	62..192	CDD:295365
		PLN02866	67..929	CDD:215467	41/201 (20%)
		PH_PLD	180..309	CDD:269956
		PLDc_SF	335..475	CDD:301585
		PLDc_SF	614..806	CDD:301585	24/117 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1502
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900