Protein Alignment CG16965 and ATH1

DIOPT Version :10

• Sequence 1: NP_609528.3
• Gene: CG16965 / 34607
• FlyBaseID: FBgn0032387
• Length: 739
• Species: Drosophila melanogaster
• Sequence 2: NP_015351.1
• Gene: ATH1 / 856137
• SGDID: S000006230
• Length: 1211
• Species: Saccharomyces cerevisiae
• Alignment Length: 795
• Identity: 202/795 - (25%)
• Similarity: 306/795 - (38%)
• Gaps: 212/795 - (26%)

  Fly    28 KTHSLPSDLNF----------------------MPTLGNGHVGYTI----FGDAIFMNGVYNGAG 66
            |.:.|.||.|.                      .|.:.||::|..|    ||.|:.....|..|.
Yeast   113 KLYELLSDFNTAYYDDENMILGSNLFSKNTYSRQPYVANGYIGSRIPNIGFGYALDTLNFYTDAP 177

  Fly    67 G----------------------------NSKR-------------ARIPNWINISTEACDRFGC 90
            |                            ||..             :.||.|.|:      :|..
Yeast   178 GALNNGWPLRNHRFAGAFVSDFYCLQPKLNSTNFPELDDVGYSTVISSIPQWTNL------QFSL 236

  Fly    91 ATDS----------DVVNGTSYEMNLRDGYFRVVTT---YRGLGISVEQRTYPHKYYNRALVYEV 142
            ..||          |.|...|..::::||   :|||   :....|.|:...:.|::.:   ...|
Yeast   237 VNDSKWFNPQNVTLDDVTNYSQNLSMKDG---IVTTELDWLNSQIHVKSEIWAHRHIH---PLGV 295

  Fly   143 VANRLAGRNSRINSPKFLRLTQFAGNFSDAFDFVVVNNGSSASGNYRTLRGQTKVVE--NEQF-- 203
            |:..::.....:.|.    ......|..|..||         :.::||:...|...|  |..|
Yeast   296 VSLEISLNTDHLPSD----FDSLDVNIWDILDF---------NTSHRTVLHSTGTDEKNNAVFMI 347

  Fly   204 -QPD--PQEIFVLFS------ESLEQPLELQWPTWQDQLS---HRVIIAIDRDESVT-------- 248
             |||  |.....::|      |:...|:.......:..:|   :.||:..|:.:.:.
Yeast   348 VQPDNVPSSNCAIYSTCTVKYENSTNPINSSESFEEKDVSSNIYNVILTEDQPKIIVHKYVGIMS 412

  Fly   249 -----RKELQD--------VLQLSS----DNLLQKHSQSWNSFWDDEFSIEIKGDALELSQIVNA 296
                 .||.||        ::.|:|    :.||..|.::|...::|.| |||..|:| |.....:
Yeast   413 TEFNKNKEQQDNTNIGLAKMIALNSKGNYEKLLSSHKRAWYDLYNDAF-IEIPSDSL-LEMTARS 475

  Fly   297 GIFYIVSSLPSLETNQKNELFYGLSPTGLGRGNLEAD-YQGHNFWDTEIWMLPIVSLFGLDYAKE 360
            .:|:::::......:....|..|:|       .|.:| |.|..|||.:|||.|.:..|..:.|:.
Yeast   476 SLFHLLANTRDYNVSSDRGLPVGVS-------GLSSDSYGGMVFWDADIWMEPALLPFFPNVAQN 533

  Fly   361 VLGYRSRKLEAAKYHANATGYKGARFPWESA-YTGTEVTNPCCPEVAEQEIHISPDISFALQKFF 424
            :..||:.....||.:|...||.||.:||.|. |.....|.||    .:.|.||:.|::.|....:
Yeast   534 MNNYRNATHSQAKLNAEKYGYPGAIYPWTSGKYANCTSTGPC----VDYEYHINVDVAMASFSIY 594

  Fly   425 AQSN---DSEWTCGTAWPITADVADFLVSRATCDDSTKTCHLLNVMGPDEDHPNVNDNVYTNAVS 486
            ...:   |.|:...|.|||..:.|.|..:....:.|.......|:..|||...::|:..:|||..
Yeast   595 LNGHEGIDDEYLRYTTWPIIKNAAQFFTAYVKYNSSLGLYETYNLTDPDEFANHINNGAFTNAGI 659

  Fly   487 KIALNFAEWLAKHCGNASTERLEKWREVSDGLVILRDESLNYHPEYAGYVRDTIIKQADTILLGY 551
            |..|.:|..:..|.|....   .||.|:|..:.|.|..| |...||:|......|||||..|:.|
Yeast   660 KTLLKWATDIGNHLGEVVD---PKWSEISKDIYIPRSSS-NITLEYSGMNSSVEIKQADVTLMVY 720

  Fly   552 PLNF--DKS--STHINDLRFYANVTRESGPAMTWSMFAA------NYLRNLQLTLANEYFERGYK 606
            ||.:  |:|  :..|.||.:|:.....||||||:.:|.|      |:..:.|..|        ||
Yeast   721 PLGYINDESILNNAIKDLYYYSERQSASGPAMTYPVFVAAAAGLLNHGSSSQSYL--------YK 777

  Fly   607 S---YVRPEFKVWSETPIGYDGSANFLT-GI-----------GGFLQALIFGYGGLDFG-RTDDD 655
            |   |:|..|..:||     ....|||| |:           |||||:::||..|:.:. ..|.|
Yeast   778 SVLPYLRAPFAQFSE-----QSDDNFLTNGLTQPAFPFLTANGGFLQSILFGLTGIRYSYEVDPD 837

  Fly   656 -----QFLMFFGISL 665
                 :.|.|..|.|
Yeast   838 TKKINRLLRFNPIEL 852

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG16965	NP_609528.3	ATH1	41..>551	CDD:441163	149/613 (24%)
ATH1	NP_015351.1	ATH1	149..>720	CDD:441163	149/612 (24%)